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  4. Recombinant Human N-alpha-acetyltransferase 20 (NAA20)

Recombinant Human N-alpha-acetyltransferase 20 (NAA20)

  • 中文名称：
    人NAA20重组蛋白
  • 货号：
    CSB-YP015472HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人NAA20重组蛋白
  • 货号：
    CSB-EP015472HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人NAA20重组蛋白
  • 货号：
    CSB-EP015472HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人NAA20重组蛋白
  • 货号：
    CSB-BP015472HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人NAA20重组蛋白
  • 货号：
    CSB-MP015472HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NAA20
  • Uniprot No.：
  • 别名：
    NAA20; NAT5; N-alpha-acetyltransferase 20; EC 2.3.1.254; Methionine N-acetyltransferase; N-acetyltransferase 5; N-terminal acetyltransferase B complex catalytic subunit NAA20; N-terminal acetyltransferase B complex catalytic subunit NAT5; NatB complex subunit NAT5; NatB catalytic subunit
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-178
  • 氨基酸序列
    MTTLRAFTCD DLFRFNNINL DPLTETYGIP FYLQYLAHWP EYFIVAEAPG GELMGYIMGK AEGSVAREEW HGHVTALSVA PEFRRLGLAA KLMELLEEIS ERKGGFFVDL FVRVSNQVAV NMYKQLGYSV YRTVIEYYSA SNGEPDEDAY DMRKALSRDT EKKSIIPLPH PVRPEDIE
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration.
  • 基因功能参考文献：
    1. The human NatB complex composed of Naa20 (NAT3) and Naa25 (MDM20) N-terminally acetylates Met-Glu-, Met-Asp-, Met-Asn- and Met-Gln- N-termini, and is important for the structure and function of actomyosin fibers and for proper cellular migration. PMID: 22814378
    2. Human N-acetyltransferase complexe NatB consists of human N-acetyltransferase 3 and human MDM20. hNAT3 knockdown results in an increase in G(0)/G(1)-phase cells. PMID: 18570629
    3. hNat3 (NAT5) is the catalytic subunit and hMdm20 the auxiliary subunit of the human NatB N-terminal acetyltransferase complex. This ribosome associated complex acetylates nascent Met-Asp/Glu- polypeptides. PMID: 18570629
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Acetyltransferase family, ARD1 subfamily
  • 数据库链接：

    HGNC: 15908

    OMIM: 610833

    KEGG: hsa:51126

    STRING: 9606.ENSP00000335636

    UniGene: Hs.368783