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  4. Recombinant Human LisH domain-containing protein FOPNL (FOPNL)

Recombinant Human LisH domain-containing protein FOPNL (FOPNL)

  • 中文名称：
    人FOPNL重组蛋白
  • 货号：
    CSB-YP836267HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人FOPNL重组蛋白
  • 货号：
    CSB-EP836267HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人FOPNL重组蛋白
  • 货号：
    CSB-EP836267HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人FOPNL重组蛋白
  • 货号：
    CSB-BP836267HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人FOPNL重组蛋白
  • 货号：
    CSB-MP836267HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    FOPNL
  • Uniprot No.：
  • 别名：
    FOPNL; C16orf63; FOR20; PHSECRG2LisH domain-containing protein FOPNL; FGFR1OP N-terminal-like protein; FOP-related protein of 20 kDa
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-174
  • 氨基酸序列
    MATVAELKAV LKDTLEKKGV LGHLKARIRA EVFNALDDDR EPRPSLSHEN LLINELIREY LEFNKYKYTA SVLIAESGQP VVPLDRQFLI HELNAFEESK DNTIPLLYGI LAHFLRGTKD GIQNAFLKGP SLQPSDPSLG RQPSRRKPMD DHLRKEEQKS TNIEDLHVSQ AVNR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in the biogenesis of cilia. Required for the recruitment of PLK1 to centrosomes and S phase progression.
  • 基因功能参考文献：
    1. The S100A6 interacts with FOR20 and related centrosomal proteins through a conserved N-terminal domain, suggesting a novel Ca(2+)-dependent regulation of centrosomal function. PMID: 28765046
    2. The results suggested that the centrosomal protein FOR20 is a new member of the microtubule-associated protein family and that it regulates the assembly and dynamics of microtubules while interacting with tubulin. PMID: 28694353
    3. The depletion of FOR20 (FOP-related protein of 20 kDa), a conserved centrosomal protein, inhibits S-phase progression and prevents targeting of Plk1 (polo-like kinase 1) to centrosomes, where FOR20 interacts with Plk1. PMID: 24018379
    4. Microdeletions at 16p13.11 are associated with a predisposition to idiopathic generalized epilepsy. PMID: 19843651
  • 亚细胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic granule. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite.
  • 蛋白家族：
    FGFR1OP family
  • 组织特异性：
    Widely expressed. Detected in brain, heart, kidney, liver, lung, skeletal muscle, placenta and intestine.
  • 数据库链接：

    HGNC: 26435

    OMIM: 617149

    KEGG: hsa:123811

    STRING: 9606.ENSP00000255759

    UniGene: Hs.514179