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  4. Recombinant Human Leucine-rich repeat transmembrane protein FLRT1 (FLRT1), partial

Recombinant Human Leucine-rich repeat transmembrane protein FLRT1 (FLRT1), partial

  • 中文名称：
    人FLRT1重组蛋白
  • 货号：
    CSB-YP865196HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人FLRT1重组蛋白
  • 货号：
    CSB-EP865196HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人FLRT1重组蛋白
  • 货号：
    CSB-EP865196HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人FLRT1重组蛋白
  • 货号：
    CSB-BP865196HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人FLRT1重组蛋白
  • 货号：
    CSB-MP865196HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    FLRT1
  • Uniprot No.：
  • 别名：
    Fibronectin-like domain containing leucine rich transmembrane protein 1; Fibronectin-like domain-containing leucine-rich transmembrane protein 1; FLRT1; FLRT1_HUMAN; Leucine rich repeat transmembrane protein FLRT1; Leucine-rich repeat transmembrane protein FLRT1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in fibroblast growth factor-mediated signaling cascades that lead to the activation of MAP kinases. Promotes neurite outgrowth via FGFR1-mediated activation of downstream MAP kinases. Promotes an increase both in neurite number and in neurite length. May play a role in cell-cell adhesion and cell guidance via its interaction with ADGRL1/LPHN1 and ADGRL3.
  • 基因功能参考文献：
    1. the phosphorylation state of FLRT1, which is itself FGFR1 dependent, may play a critical role in the potentiation of FGFR1 signalling and may also depend on a SFK-dependent phosphorylation mechanism acting via the FGFR PMID: 20421966
  • 亚细胞定位：
    Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane. Cytoplasmic vesicle membrane. Cytoplasm, perinuclear region. Cell junction, focal adhesion. Secreted. Cell projection, neuron projection. Cell junction.
  • 组织特异性：
    Expressed in kidney and brain.
  • 数据库链接：

    HGNC: 3760

    OMIM: 604806

    KEGG: hsa:23769

    STRING: 9606.ENSP00000246841

    UniGene: Hs.584876