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  4. Recombinant Human Leucine-rich repeat LGI family member 3 (LGI3)

Recombinant Human Leucine-rich repeat LGI family member 3 (LGI3)

  • 中文名称：
    人LGI3重组蛋白
  • 货号：
    CSB-YP822680HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人LGI3重组蛋白
  • 货号：
    CSB-EP822680HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人LGI3重组蛋白
  • 货号：
    CSB-EP822680HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人LGI3重组蛋白
  • 货号：
    CSB-BP822680HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人LGI3重组蛋白
  • 货号：
    CSB-MP822680HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    LGI3
  • Uniprot No.：
  • 别名：
    Leucine rich repeat LGI family member 3; Leucine-rich glioma inactivated protein 3; Leucine-rich glioma-inactivated protein 3; Leucine-rich repeat LGI family member 3; LGI1 like protein 4; LGI1-like protein 4; LGI3; LGI3_HUMAN; LGIL4
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    31-548
  • 氨基酸序列
    KRPPKTPPCP PSCSCTRDTA FCVDSKAVPR NLPSEVISLT LVNAAFSEIQ DGAFSHLPLL QFLLLNSNKF TLIGDNAFTG LSHLQYLFIE NNDIWALSKF TFRGLKSLTH LSLANNNLQT LPRDIFRPLD ILNDLDLRGN SLNCDCKVKW LVEWLAHTNT TVAPIYCASP PRFQEHKVQD LPLREFDCIT TDFVLYQTLA FPAVSAEPFL YSSDLYLALA QPGVSACTIL KWDYVERQLR DYDRIPAPSA VHCKPMVVDS QLYVVVAQLF GGSYIYHWDP NTTRFTRLQD IDPQRVRKPN DLEAFRIDGD WYFAVADSSK AGATSLYRWH QNGFYSHQAL HPWHRDTDLE FVDGEGKPRL IVSSSSQAPV IYQWSRTQKQ FVAQGEVTQV PDAQAVKHFR AGRDSYLCLS RYIGDSKILR WEGTRFSEVQ ALPSRGSLAL QPFLVGGRRY LALGSDFSFT QIYQWDEGRQ KFVRFQELAV QAPRAFCYMP AGDAQLLLAP SFKGQTLVYR HIVVDLSA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May participate in the regulation of neuronal exocytosis.
  • 基因功能参考文献：
    1. The expression of LGI3 was significantly associated with the prognosis of brain, colorectal and lung cancer. PMID: 29257304
    2. Leucine-rich glioma inactivated 3 is a cytokine in human skin that promotes melanin production. PMID: 24903553
    3. LGI3 was mostly expressed in the granular layer of the epidermis of human skin. PMID: 23815230
  • 亚细胞定位：
    Secreted. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Cell junction, synapse, synaptosome.
  • 组织特异性：
    Widely expressed, with highest levels in brain and lung.
  • 数据库链接：

    HGNC: 18711

    OMIM: 608302

    KEGG: hsa:203190

    STRING: 9606.ENSP00000302297

    UniGene: Hs.33470