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  4. Recombinant Human Insulin growth factor-like family member 1 (IGFL1)

Recombinant Human Insulin growth factor-like family member 1 (IGFL1)

In Stock
  • 中文名称：
    人IGFL1重组蛋白
  • 货号：
    CSB-EP764932HU
  • 规格：
    ￥1836
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
  • Uniprot No.：
  • 别名：
    IGFL1; UNQ644/PRO1274; Insulin growth factor-like family member 1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 来源：
    E.coli
  • 分子量：
    16.8 kDa
  • 表达区域：
    25-110aa
  • 氨基酸序列
    APVAPMTPYLMLCQPHKRCGDKFYDPLQHCCYDDAVVPLARTQTCGNCTFRVCFEQCCPWTFMVKLINQNCDSARTSDDRLCRSVS
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer，50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 产品描述：

    The N-terminal 10xHis tag and C-terminal Myc tag was fused to the gene fragment corresponding to the 25-110aa of the human IGFL1 protein and then was cloned into an expression vector. The expression vector was transformed into the E.coli for expression. The generated product was purified and separated to obtain the recombinant human IGFL1 protein. Its purity is higher than 85%. This recombinant human IGFL1 protein showed an apparent molecular weight of about 19 kDa under SDS-PAGE condition.

    IGFL1 is gene encoding protein named Insulin growth factor-like family member 1. This gene belongs to IGFL family which play critical roles in cellular energy metabolism and in growth and development, especially prenatal growth. The protein encoded by IGFL1 gene is synthesized as a precursor protein and is proteolytically cleaved to form a secreted mature peptide. This protein can be detected in ovary and spinal cord. Murine insulin growth factor-like (IGFL) and human IGFL1 proteins are induced in inflammatory skin conditions and bind to a novel tumor necrosis factor receptor family member (IGFLR1).

  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probable ligand of the IGFLR1 cell membrane receptor.
  • 基因功能参考文献：
    1. Murine insulin growth factor-like (IGFL) and human IGFL1 proteins are induced in inflammatory skin conditions and bind to a novel tumor necrosis factor receptor family member, IGFLR1. PMID: 21454693
    2. The -1245 A-allele of the IGF1 promoter single nucleotide polymorphism is associated with a small head size and less brain sparing in small for gestational age born subjects PMID: 19147602
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    IGFL family
  • 组织特异性：
    Detected in ovary and spinal cord.
  • 数据库链接：

    HGNC: 24093

    OMIM: 610544

    KEGG: hsa:374918

    UniGene: Hs.546554