Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Human Immediate early response gene 2 protein (IER2)

Recombinant Human Immediate early response gene 2 protein (IER2)

  • 中文名称：
    人IER2重组蛋白
  • 货号：
    CSB-YP871574HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人IER2重组蛋白
  • 货号：
    CSB-EP871574HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人IER2重组蛋白
  • 货号：
    CSB-EP871574HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人IER2重组蛋白
  • 货号：
    CSB-BP871574HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人IER2重组蛋白
  • 货号：
    CSB-MP871574HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    IER2
  • Uniprot No.：
  • 别名：
    IER2; ETR101; PIP92; Immediate early response gene 2 protein; Protein ETR101
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-223
  • 氨基酸序列
    MEVQKEAQRI MTLSVWKMYH SRMQRGGLRL HRSLQLSLVM RSARELYLSA KVEALEPEVS LPAALPSDPR LHPPREAEST AETATPDGEH PFPEPMDTQE APTAEETSAC CAPRPAKVSR KRRSSSLSDG GDAGLVPSKK ARLEEKEEEE GASSEVADRL QPPPAQAEGA FPNLARVLQR RFSGLLNCSP AAPPTAPPAC EAKPACRPAD SMLNVLVRAV VAF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    DNA-binding protein that seems to act as a transcription factor. Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells. May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo. Promotes cell motility, seems to stimulate tumor metastasis.
  • 基因功能参考文献：
    1. IER2 promoted hepatocellular carcinoma cell adhesion and motility by directly increasing ITGB1 expression and subsequently activating the ITGB1FAKSrcpaxillin signal pathway. PMID: 27840969
    2. results from western blot analysis showed that the activity of the focal adhesion kinase (FAK) can be regulated by IER2. PMID: 26260137
    3. ectopic Ier2 expression promoted the motility and invasiveness of poorly metastatic 1AS pancreatic tumor cells in vitro PMID: 22120713
    4. the functioning of ETR101 as a transcriptional activator for the gene ISYNA1 PMID: 19584537
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    IER family
  • 组织特异性：
    Expressed in activated T-cells (at protein level). Expression increases in metastatic tumor cells (at protein level).
  • 数据库链接：

    HGNC: 28871

    KEGG: hsa:9592

    STRING: 9606.ENSP00000292433

    UniGene: Hs.501629