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  4. Recombinant Human Homeobox protein unc-4 homolog (UNCX)

Recombinant Human Homeobox protein unc-4 homolog (UNCX)

  • 中文名称：
    人UNCX重组蛋白
  • 货号：
    CSB-YP025640HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人UNCX重组蛋白
  • 货号：
    CSB-EP025640HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人UNCX重组蛋白
  • 货号：
    CSB-EP025640HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人UNCX重组蛋白
  • 货号：
    CSB-BP025640HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人UNCX重组蛋白
  • 货号：
    CSB-MP025640HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    UNCX
  • Uniprot No.：
  • 别名：
    Homeobox protein unc-4 homolog; Homeobox protein Uncx4.1; tcag7.1272; UNC homeobox; Unc4.1 homeobox; UNC4_HUMAN; Uncx; UNCX4.1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-531
  • 氨基酸序列
    MMDGRLLEHP HAQFGGSLGG VVGFPYPLGH HHVYELAGHQ LQSAAAAASV PFSIDGLLGG SCAAAASVVN PTPLLPAACG VGGDGQPFKL SDSGDPDKES PGCKRRRTRT NFTGWQLEEL EKAFNESHYP DVFMREALAL RLDLVESRVQ VWFQNRRAKW RKKENTKKGP GRPAHNSHPT TCSGEPMDPE EIARKELEKM EKKKRKHEKK LLKSQGRHLH SPGGLSLHSA PSSDSDSGGG GLSPEPPEPP PPAAKGPGAH ASGAAGTAPA PPGEPPAPGT CDPAFYPSQR SGAGPQPRPG RPADKDAASC GPGAAVAAVE RGAAGLPKAS PFSVESLLSD SPPRRKAASN AAAAAAAGLD FAPGLPCAPR TLIGKGHFLL YPITQPLGFL VPQAALKGGA GLEPAPKDAP PAPAVPPAPP AQASFGAFSG PGGAPDSAFA RRSPDAVASP GAPAPAPAPF RDLASAAATE GGGGDCADAG TAGPAPPPPA PSPRPGPRPP SPAEEPATCG VPEPGAAAGP SPPEGEELDM D
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions.
  • 基因功能参考文献：
    1. our findings suggest a novel leukemogenic role of UNCX, associated with epigenetic modifications and with impaired cell proliferation and differentiation in AML. PMID: 28411256
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Paired homeobox family, Unc-4 subfamily
  • 数据库链接：

    HGNC: 33194

    KEGG: hsa:340260

    STRING: 9606.ENSP00000314480