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  4. Recombinant Human Homeobox protein notochord (NOTO)

Recombinant Human Homeobox protein notochord (NOTO)

  • 中文名称：
    人NOTO重组蛋白
  • 货号：
    CSB-YP015954HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人NOTO重组蛋白
  • 货号：
    CSB-EP015954HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人NOTO重组蛋白
  • 货号：
    CSB-EP015954HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人NOTO重组蛋白
  • 货号：
    CSB-BP015954HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人NOTO重组蛋白
  • 货号：
    CSB-MP015954HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NOTO
  • Uniprot No.：
  • 别名：
    notochord homolog; flh; floating head; floating head homolog; Homeobox protein notochord; Not; Not homeodomain protein; Noto; NOTO_HUMAN; notochord homeobox; notochord homolog (Xenopus laevis); Znot
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-251
  • 氨基酸序列
    MPSPRPRGSP PPAPSGSRVR PPRSGRSPAP RSPTGPNTPR APGRFESPFS VEAILARPDP CAPAASQPSG SACVHPAFWT AASLCATGGL PWACPTSWLP AYLSVGFYPV PGPRVAPVCG LLGFGVTGLE LAHCSGLWAF PDWAPTEDLQ DTERQQKRVR TMFNLEQLEE LEKVFAKQHN LVGKKRAQLA ARLKLTENQV RVWFQNRRVK YQKQQKLRAA VTSAEAASLD EPSSSSIASI QSDDAESGVD G
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription regulator acting downstream of both FOXA2 and Brachyury (T) during notochord development. Required for node morphogenesis. Is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate. Activates the transcription of ciliary proteins C11orf97 homolog, FAM183B and SPACA9 in the embryonic ventral node.
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 31839

    KEGG: hsa:344022

    STRING: 9606.ENSP00000381486

    UniGene: Hs.694384