Recombinant Human Galectin-2 (LGALS2)
-
中文名称:人LGALS2重组蛋白
-
货号:CSB-EP012886HU
-
规格:¥1344
-
图片:
-
其他:
产品详情
-
纯度:Greater than 90% as determined by SDS-PAGE.
-
基因名:LGALS2
-
Uniprot No.:
-
别名:Beta galactoside binding lectin L14 II; Beta-galactoside-binding lectin L-14-II; CBP35; Gal-2; GAL3; GALBP; Galectin 2; Galectin-2; GALIG; HL14; Lactose binding lectin 2; Lactose-binding lectin 2; LEG2_HUMAN; LGALS2; MAC2; S Lac lectin 2; S-Lac lectin 2
-
种属:Homo sapiens (Human)
-
蛋白长度:Full Length
-
来源:E.coli
-
分子量:41.6kDa
-
表达区域:1-132aa
-
氨基酸序列MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTDKLNLHFNPRFSESTIVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDGHELTFPNRLGHSHLSYLSVRGGFNMSSFKLKE
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request. -
蛋白标签:N-terminal GST-tagged
-
产品提供形式:Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
缓冲液:Tris-based buffer,50% glycerol
-
储存条件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
-
保质期:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
-
注意事项:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
Datasheet & COA:Please contact us to get it.
相关产品
靶点详情
-
功能:This protein binds beta-galactoside. Its physiological function is not yet known.
-
基因功能参考文献:
- Study observed decreased methylation at the DHCR24 locus in offspring of women with active pregnancy eating disorders (ED) and increased methylation at the LGALS2 locus in offspring of women with past ED compared to controls. PMID: 29093763
- Data show that lactose binding to galectin-2 (Gal-2) stabilizes the lectin's conformation. PMID: 27563008
- Gal-3 was significantly downregulated only in the extravillous trophoblast of intrauterine growth restriction ( IUGR) placentas. In contrast, expressions of gal-2 and gal-13 were downregulated in both villous and extravillous trophoblast cells of IUGR placentas. PMID: 27070577
- Galectin-2 binding to different circulating human monocyte subsets depends on monocyte surface expression levels of CD14. It skews human macrophages to a M1-like proinflammatory phenotype. PMID: 25884209
- PPARG rs1152002, AGTR1 rs5186, CXCL16 rs3744700 and LGALS2 rs7291467 polymorphisms may be closely related to the development of coronary heart disease PMID: 26045830
- Lower LGALS2 gene expression is associated with acute myeloid leukemia. PMID: 25953264
- Data suggest that expression of galectin 2 and galectin 2 mRNA is down-regulated in placental extravillous trophoblast and decidua in women with pre-eclampsia as compared to women with normal term pregnancy. PMID: 25707742
- The increased circulation of galectins -2, -4 and -8 in cancer patients contributes substantially to the increased circulation of G-CSF, IL-6 and MCP-1 by interaction with the blood vascular endothelium PMID: 24384681
- Cys57Met (single-site) mutant and its monoPEGylated derivative can markedly reduce binding of galectin-2 to physiological binding sites PMID: 23581621
- results identify galectin-2 as a novel inhibitor of arteriogenesis and its modulation may constitute a new therapeutic strategy for the stimulation of arteriogenesis in patients with coronary artery disease. PMID: 21831908
- LTA and LGALS2 polymorphisms affect the subclinical phenotype of the coronary artery, which predisposes to the incidence of myocardial infarction. PMID: 22310064
- low expression of galectin-2 was significantly associated with lymph node metastasis and advanced clinical stage in patients with gastric cancer PMID: 22015694
- These results suggested differences in the inflammatory response to malaria in children and adults with polymorphisms of the galectin-2 gene. PMID: 20500087
- the LTA gene and LGALS2-C3279T are not associated with coronary artery disease PMID: 19726041
- Our case-control association study in a Japanese population showed that a single nucleotide polymorphism in LGALS2 encoding galectin-2 is significantly associated with susceptibility to myocardial infarction PMID: 15129282
- This study classifies galectin-2 as proapoptotic effector for activated T cells, raising a therapeutic perspective. PMID: 15356130
- Fasting plasma glucose and serum insulin were statistically significantly associated with LGALS2 PMID: 16468038
- Galectin 2 induces surface phosphatidylserine exposure in a carbohydrate-dependent fashion in activated, but not resting, human neutrophils and in several leukocyte cell lines. PMID: 16940423
- no significant association of allele frequency with risk of myocardial infarction PMID: 17098239
- polymorphism of LGALS2 was not associated with the severity of coronary atherosclerosis in Japanese and Korean populations PMID: 17493152
- Data show that galectin-2 SNPs are not associated with myocardial infarction in two different German populations. PMID: 17497114
- Galectin-2 was present in nuclei of Geneti-cally engineered human colon carcinoma cells with stable ectopic expression. PMID: 17999373
- Data show that genotypes for the 3279C-->T polymorphism (rs7291467) of LGALS2 was associated (P<0.05) with the prevalence of atherothrombotic cerebral infarction. PMID: 18506375
- Galectin-2 (LGALS2) 3279C/T polymorphism may be independently associated with diastolic blood pressure in patients with rheumatoid arthritis. PMID: 19330599
- Galectin-2 is strongly expressed in inflammatory skin of autoimmune-prone transgenic mice, indicating that galectin-2 is up-regulated upon experimental cutaneous inflammation. PMID: 19380789
显示更多
收起更多
-
数据库链接:
HGNC: 6562
OMIM: 150571
KEGG: hsa:3957
STRING: 9606.ENSP00000215886
UniGene: Hs.531776
Most popular with customers
-
Recombinant Human Heat-stable enterotoxin receptor (GUCY2C), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Complement component C1q receptor (CD93), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Macaca fascicularis CD93 molecule (CD93), partial (Active)
Express system: Mammalian cell
Species: Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
-
Recombinant Macaca fascicularis Zinc transporter ZIP6 isoform X1(SLC39A6),partial (Active)
Express system: Baculovirus
Species: Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
-
Recombinant Human Tumor necrosis factor ligand superfamily member 15(TNFSF15) (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)