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  4. Recombinant Human Diphosphoinositol polyphosphate phosphohydrolase 3-alpha (NUDT10)

Recombinant Human Diphosphoinositol polyphosphate phosphohydrolase 3-alpha (NUDT10)

  • 中文名称：
    人NUDT10重组蛋白
  • 货号：
    CSB-YP839873HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人NUDT10重组蛋白
  • 货号：
    CSB-EP839873HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人NUDT10重组蛋白
  • 货号：
    CSB-EP839873HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人NUDT10重组蛋白
  • 货号：
    CSB-BP839873HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人NUDT10重组蛋白
  • 货号：
    CSB-MP839873HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NUDT10
  • Uniprot No.：
  • 别名：
    5'''-P1; APS 2; APS2; Diadenosine 5' 5''' P1 P6 hexaphosphate hydrolase 3 alpha; Diadenosine 5'; Diadenosine hexaphosphate hydrolase (AMP-forming); Diphosphoinositol polyphosphate phosphohydrolase 3; alpha; Diphosphoinositol polyphosphate phosphohydrolase 3-alpha; Diphosphoinositol polyphosphate phosphohydrolase type 3 alpha; DIPP 3 alpha; DIPP 3a; DIPP-3-alpha; DIPP3 alpha; DIPP3-alpha; DIPP3a; hAps 2; hAps2; hDIPP3alpha; Nucleoside diphosphate linked moiety X motif 10; Nucleoside diphosphate-linked moiety X motif 10; NUD10_HUMAN; Nudix (nucleoside diphosphate linked moiety X) type motif 10; Nudix motif 10; Nudix type motif 10; NUDT 10; NUDT10; P6-hexaphosphate hydrolase 3-alpha
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-164
  • 氨基酸序列
    MKCKPNQTRT YDPEGFKKRA ACLCFRSERE DEVLLVSSSR YPDRWIVPGG GMEPEEEPGG AAVREVYEEA GVKGKLGRLL GVFEQNQDPK HRTYVYVLTV TELLEDWEDS VSIGRKREWF KVEDAIKVLQ CHKPVHAEYL EKLKLGGSPT NGNSMAPSSP DSDP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
  • 基因功能参考文献：
    1. The NUDT10 gene, located on chromosome X, is preferentially expressed in the testis PMID: 12105228
    2. Cloning and characterisation of NUDT10 as a diadenosine polyphosphate-metabolising Nudix hydrolase. PMID: 12121577
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Nudix hydrolase family, DIPP subfamily
  • 组织特异性：
    Mainly expressed in testis and, at lower level in brain. According to PubMed:12121577, it is widely expressed.
  • 数据库链接：

    HGNC: 17621

    OMIM: 300527

    KEGG: hsa:170685

    STRING: 9606.ENSP00000348831

    UniGene: Hs.375178