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  4. Recombinant Human Cadherin-related family member 3 (CDHR3), partial

Recombinant Human Cadherin-related family member 3 (CDHR3), partial

  • 中文名称：
    Recombinant Human Cadherin-related family member 3(CDHR3),partial,Yeast
  • 货号：
    CSB-YP747803HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Cadherin-related family member 3(CDHR3),partial,Yeast
  • 货号：
    CSB-EP747803HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Cadherin-related family member 3(CDHR3),partial,Yeast
  • 货号：
    CSB-EP747803HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Cadherin-related family member 3(CDHR3),partial,Yeast
  • 货号：
    CSB-BP747803HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Cadherin-related family member 3(CDHR3),partial,Yeast
  • 货号：
    CSB-MP747803HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CDHR3
  • Uniprot No.：
  • 别名：
    Cadherin-like protein 28; Cadherin-related family member 3; Cdhr3; CDHR3_HUMAN; FLJ43271; Hypothetical protein FLJ23834; Hypothetical protein LOC222256; MGC133292; MGC133293
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.; (Microbial infection) Acts as a receptor for rhinovirus C.
  • 基因功能参考文献：
    1. Our study supports the concept that the CDHR3 variant is an important susceptibility factor for severe adult asthma in individuals who develop the disease in early life. PMID: 28318885
    2. CDHR3 is a susceptibility locus for early childhood Asthma with severe exacerbations. PMID: 26270739
    3. the asthma susceptibility gene product CDHR3 mediates RV-C entry into host cells, and suggest that rs6967330 mutation could be a risk factor for RV-C wheezing illnesses. PMID: 25848009
    4. the role of CDHR3 variants in the development of asthma with severe exacerbations based on genome-wide association study in Denmark PMID: 24241537
  • 相关疾病：
    Asthma susceptibility may be associated with variations affecting the gene represented in this entry in early childhood asthma with severe exacerbations occurring between 2 and 6 years of age.
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Expressed in bronchial epithelium from adults and in fetal lung tissue.
  • 数据库链接：

    HGNC: 26308

    OMIM: 615610

    KEGG: hsa:222256

    STRING: 9606.ENSP00000325954

    UniGene: Hs.150120