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  4. Recombinant Human Apolipoprotein L6 (APOL6)

Recombinant Human Apolipoprotein L6 (APOL6)

  • 中文名称：
    Recombinant Human Apolipoprotein L6(APOL6),Yeast
  • 货号：
    CSB-YP861156HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Apolipoprotein L6(APOL6),Yeast
  • 货号：
    CSB-EP861156HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Apolipoprotein L6(APOL6),Yeast
  • 货号：
    CSB-EP861156HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Apolipoprotein L6(APOL6),Yeast
  • 货号：
    CSB-BP861156HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Apolipoprotein L6(APOL6),Yeast
  • 货号：
    CSB-MP861156HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    APOL6
  • Uniprot No.：
  • 别名：
    2310076O14Rik; APOL VI; ApoL-VI; APOL6; APOL6_HUMAN; Apolipoprotein L VI; Apolipoprotein L; 6; Apolipoprotein L-VI; Apolipoprotein L6; APOLVI; DKFZp667M075; FLJ38562; FLJ90164; MGC57495
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-343
  • 氨基酸序列
    MDNQAERESE AGVGLQRDED DAPLCEDVEL QDGDLSPEEK IFLREFPRLK EDLKGNIDKL RALADDIDKT HKKFTKANMV ATSTAVISGV MSLLGLALAP ATGGGSLLLS TAGQGLATAA GVTSIVSGTL ERSKNKEAQA RAEDILPTYD QEDREDEEEK ADYVTAAGKI IYNLRNTLKY AKKNVRAFWK LRANPRLANA TKRLLTTGQV SSRSRVQVQK AFAGTTLAMT KNARVLGGVM SAFSLGYDLA TLSKEWKHLK EGARTKFAEE LRAKALELER KLTELTQLYK SLQQKVRSRA RGVGKDLTGT CETEAYWKEL REHVWMWLWL CVCLCVCVYV QFT
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles.
  • 基因功能参考文献：
    1. Polymorphisms in FABP2 and APOL6, located at the predicted miRNAs binding sites, are identified to contribute to susceptibility to MetS in the Chinese Han population. PMID: 23911300
    2. results suggest that ApoL6 regulates both apoptosis and autophagy in SMCs. IFNgamma-initiated, ApoL6-induced apoptosis in vascular cells may be an important factor causing plaque instability PMID: 21646352
    3. Apolipoprotein l6 is a novel proapoptotic Bcl-2 homology 3-only protein that induces mitochondria-mediated apoptosis in cancer cells PMID: 15671246
    4. APOL6 has been found only in humans PMID: 11374903
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Apolipoprotein L family
  • 组织特异性：
    Widely expressed; highly expressed in the uterus, fetal brain and spinal cord, also detected in heart, liver, lung, colon, spleen, thymus, prostate, placenta, adrenal gland, salivary and mammary gland.
  • 数据库链接：

    HGNC: 14870

    OMIM: 607256

    KEGG: hsa:80830

    STRING: 9606.ENSP00000386280

    UniGene: Hs.257352