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  4. Recombinant Human Alkylglycerol monooxygenase (AGMO), partial

Recombinant Human Alkylglycerol monooxygenase (AGMO), partial

  • 中文名称：
    Recombinant Human Alkylglycerol monooxygenase(AGMO),partial,Yeast
  • 货号：
    CSB-YP747780HU1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Alkylglycerol monooxygenase(AGMO),partial,Yeast
  • 货号：
    CSB-EP747780HU1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Alkylglycerol monooxygenase(AGMO),partial,Yeast
  • 货号：
    CSB-EP747780HU1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Alkylglycerol monooxygenase(AGMO),partial,Yeast
  • 货号：
    CSB-BP747780HU1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Alkylglycerol monooxygenase(AGMO),partial,Yeast
  • 货号：
    CSB-MP747780HU1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    AGMO
  • Uniprot No.：
  • 别名：
    AGMO; TMEM195; Alkylglycerol monooxygenase; Transmembrane protein 195
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids. Ether lipids are essential components of brain membranes.
  • 基因功能参考文献：
    1. We identified homozygous and heterozygous mutations of the alkylglycerol monooxygenase (AGMO) gene (MIM 613738) as the likely cause of visceral leishmaniasis relapse in 3 families. PMID: 28586473
    2. An AGMO mutation was found in a Saudi family underlying primary microcephaly and intellectual disability. PMID: 27000257
    3. Among all of the acidic residues within the eight-histidine motif, only mutation of Glu137 to alanine led to an 18-fold increase in the Michaelis-Menten constant for tetrahydrobiopterin, suggesting a role in tetrahydrobiopterin interaction PMID: 22220568
    4. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20571754
    5. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20613766
    6. Transmembrane protein 195 has tetrahydrobiopterin-dependent alkylglycerol monooxygenase activity (also known as glyceryl-ether monooxygenase activity, E.C. 1.14.16.5). PMID: 20643956
    7. Observational study of gene-disease association. (HuGE Navigator) PMID: 20419449
    8. Meta-analysis and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20081858

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  • 亚细胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Sterol desaturase family, TMEM195 subfamily
  • 数据库链接：

    HGNC: 33784

    OMIM: 613738

    KEGG: hsa:392636

    STRING: 9606.ENSP00000341662

    UniGene: Hs.670634