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  4. Recombinant Helicobacter pylori Ferric uptake regulation protein (fur)

Recombinant Helicobacter pylori Ferric uptake regulation protein (fur)

  • 中文名称：
    幽门螺旋杆菌fur重组蛋白
  • 货号：
    CSB-YP517883HUV
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    幽门螺旋杆菌fur重组蛋白
  • 货号：
    CSB-EP517883HUV
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    幽门螺旋杆菌fur重组蛋白
  • 货号：
    CSB-EP517883HUV-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    幽门螺旋杆菌fur重组蛋白
  • 货号：
    CSB-BP517883HUV
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    幽门螺旋杆菌fur重组蛋白
  • 货号：
    CSB-MP517883HUV
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    fur
  • Uniprot No.：
  • 别名：
    fur; HP_1027Ferric uptake regulation protein; Ferric uptake regulator
  • 种属：
    Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-150
  • 氨基酸序列
    MKRLETLESI LERLRMSIKK NGLKNSKQRE EVVSVLYRSG THLSPEEITH SIRQKDKNTS ISSVYRILNF LEKENFICVL ETSKSGRRYE IAAKEHHDHI ICLHCGKIIE FADPEIENRQ NEVVKKYQAK LISHDMKMFV WCKECQESEC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
  • 基因功能参考文献：
    1. Fur R88H mutation conferred increased resistance to high-salt conditions and oxidative stress in Helicobacter pylori. PMID: 26438795
    2. Only one binding site is absolutely required for DNA binding and is responsible for the conformational changes of Fur upon metal binding. PMID: 21208302
    3. versatile regulator involved in many pathways essential for gastric colonization. PMID: 15699202
    4. H. pylori Fur is a versatile regulator involved in many pathways essential for gastric colonization, including superoxide stress defense. PMID: 15901691
    5. This paper describes the biochemical characterization of the native ferric uptake regulator from Helicobacter pylori (HpFur): oligomeric state, metal content, and characterization of a structural metal-binding site. PMID: 19419176

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Fur family
  • 数据库链接：

    KEGG: heo:C694_05315

    STRING: 85962.HP1027