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  4. Recombinant Escherichia coli Transcriptional regulatory protein qseB (qseB)

Recombinant Escherichia coli Transcriptional regulatory protein qseB (qseB)

  • 中文名称：
    大肠杆菌qseB重组蛋白
  • 货号：
    CSB-YP345968ENV
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大肠杆菌qseB重组蛋白
  • 货号：
    CSB-EP345968ENV
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大肠杆菌qseB重组蛋白
  • 货号：
    CSB-EP345968ENV-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大肠杆菌qseB重组蛋白
  • 货号：
    CSB-BP345968ENV
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大肠杆菌qseB重组蛋白
  • 货号：
    CSB-MP345968ENV
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    qseB
  • Uniprot No.：
  • 别名：
    qseB; ygiX; b3025; JW2993; Transcriptional regulatory protein QseB
  • 种属：
    Escherichia coli (strain K12)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-219
  • 氨基酸序列
    MRILLIEDDM LIGDGIKTGL SKMGFSVDWF TQGRQGKEAL YSAPYDAVIL DLTLPGMDGR DILREWREKG QREPVLILTA RDALAERVEG LRLGADDYLC KPFALIEVAA RLEALMRRTN GQASNELRHG NVMLDPGKRI ATLAGEPLTL KPKEFALLEL LMRNAGRVLS RKLIEEKLYT WDEEVTSNAV EVHVHHLRRK LGSDFIRTVH GIGYTLGEK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Member of a two-component regulatory system QseB/QseC. Activates the flagella regulon by activating transcription of FlhDC. Currently it is not known whether this effect is direct or not.
  • 基因功能参考文献：
    1. study concludes that cross talk between the regulatory systems for virulence and metabolism of aromatic amines may depend upon the ability of QseBC and, to a lesser extent QseF, to regulate feaR as well as genes directly involved in virulence PMID: 29038253
    2. All components of the QseBC and PmrAB two-component systems (TCSs) are required for proper response to ferric iron. PMID: 28074004
    3. The presence of one sensor kinase, QseC, is required to regulate the interaction between the other sensor kinase, PmrB and the response regulators from both systems, QseB and PmrA, effectively creating a "four-component" system required for virulence. PMID: 28396353
    4. Near-parental level of motility, ability to respond to norepinephrine, and enhanced expression of locus of enterocyte effacement and curli genes might in part be responsible for increased colonization and fecal shedding of the qseBC mutant in calves. PMID: 24413602
    5. The s discovered that QseC has phosphatase activity required for QseB dephosphorylation. PMID: 19703104

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  • 亚细胞定位：
    Cytoplasm.
  • 数据库链接：

    KEGG: ecj:JW2993

    STRING: 316385.ECDH10B_3199