Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Escherichia coli Aerobic respiration control protein ArcA (arcA)

Recombinant Escherichia coli Aerobic respiration control protein ArcA (arcA)

  • 中文名称：
    Recombinant Escherichia coli Aerobic respiration control protein ArcA(arcA),Yeast
  • 货号：
    CSB-YP359331ENV
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Escherichia coli Aerobic respiration control protein ArcA(arcA),Yeast
  • 货号：
    CSB-EP359331ENV
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Escherichia coli Aerobic respiration control protein ArcA(arcA),Yeast
  • 货号：
    CSB-EP359331ENV-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Escherichia coli Aerobic respiration control protein ArcA(arcA),Yeast
  • 货号：
    CSB-BP359331ENV
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Escherichia coli Aerobic respiration control protein ArcA(arcA),Yeast
  • 货号：
    CSB-MP359331ENV
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    arcA
  • Uniprot No.：
  • 别名：
    arcA; cpxC; dye; fexA; msp; seg; sfrA; b4401; JW4364Aerobic respiration control protein ArcA; Dye resistance protein
  • 种属：
    Escherichia coli (strain K12)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-238
  • 氨基酸序列
    MQTPHILIVE DELVTRNTLK SIFEAEGYDV FEATDGAEMH QILSEYDINL VIMDINLPGK NGLLLARELR EQANVALMFL TGRDNEVDKI LGLEIGADDY ITKPFNPREL TIRARNLLSR TMNLGTVSEE RRSVESYKFN GWELDINSRS LIGPDGEQYK LPRSEFRAML HFCENPGKIQ SRAELLKKMT GRELKPHDRT VDVTIRRIRK HFESTPDTPE IIATIHGEGY RFCGDLED
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. Controls the resistance of E.coli to dyes; required for expression of the alkaline phosphatase and sex factor F genes; It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expression of genes of aerobic function. Activates the transcription of the plfB operon by binding to its promoter.
  • 基因功能参考文献：
    1. The combined results indicate that ArcA controls metabolism, chemotaxis, and motility contributing to the pathogenicity of Avian pathogenic Escherichia coli PMID: 26099584
    2. We propose that this plasticity in ArcA binding site architecture provides both an efficient means of encoding binding sites for ArcA, sigma(70)-RNAP and perhaps other transcription factors PMID: 24146625
    3. The deletion of arcA results in a decrease of repression on transcription of tricarboxylic acid cycle genes under glucose abundant conditions, without significantly affecting the glyoxylate pathway activity. PMID: 21481254
    4. the activity of the regulator ArcA correlated with aerobiosis but not with the redox state of the ubiquinone pool, challenging the idea that ArcA activity is inhibited by oxidized ubiquinone. PMID: 21252224
    5. fadH promoter is regulated by three independent regulators, the fatty acid degradation FadR repressor, the oxygen-responsive ArcA-ArcB two-component system, and the cyclic AMP receptor protein-cyclic AMP. PMID: 20622065
    6. The ArcBA two-component system of Escherichia coli is regulated by the redox state of both the ubiquinone and the menaquinone pool. PMID: 19933363
    7. Knockout of ArcA-dependent redox regulation, however, increased the aerobic tricarboxylic acid (TCA) cycle activity by over 60%. PMID: 15838044
    8. ArcB/ArcA/RssB system is involved in sigmaS induction during entry into starvation conditions. PMID: 16291649
    9. must be regulatory factors other than ArcB interacting with ArcA to control flagella genes PMID: 17213678
    10. Activation of ArcA facilitates pIV-dependent induction of psp expression. PMID: 19682256
    11. These data show that the acetyl phosphate dependent ArcA phosphorylation route does not seem to play a significant role under physiological conditions. PMID: 19851741

    显示更多

    收起更多

  • 亚细胞定位：
    Cytoplasm.
  • 数据库链接：

    KEGG: ecj:JW4364

    STRING: 316385.ECDH10B_4559