Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Drosophila melanogaster Serine/threonine-protein kinase tricorner (trc)

Recombinant Drosophila melanogaster Serine/threonine-protein kinase tricorner (trc)

  • 中文名称：
    黑腹果蝇trc重组蛋白
  • 货号：
    CSB-YP882036DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇trc重组蛋白
  • 货号：
    CSB-EP882036DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇trc重组蛋白
  • 货号：
    CSB-EP882036DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇trc重组蛋白
  • 货号：
    CSB-BP882036DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇trc重组蛋白
  • 货号：
    CSB-MP882036DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    trc
  • Uniprot No.：
  • 别名：
    trc; CG8637; Serine/threonine-protein kinase tricorner; EC 2.7.11.1; NDR protein kinase; Serine/threonine-protein kinase 38-like
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-463
  • 氨基酸序列
    MMSSRTQDAD GASIRFSDHT LDKATKAKVT LENYYSNLVT QYGERKQRLA KLEAQLKDES LSEAQRQEKR LQHAQKETEY LRLKRLRLGV EDFEALKVIG RGAFGEVRLV QKKDTGHVYA MKVLRKADML EKEQVAHVRA ERDVLVEADH QWVVKMYYSF QDPVNLYLIM EFLPGGDMMT LLMKKDTLSE EGTQFYISET ALAIDSIHKL GFIHRDIKPD NLLLDARGHL KLSDFGLCTG LKKSHRTDFY RDLSQAKPSD FIGTCASLSC SPMDSKRRAE SWKRNRRALA YSTVGTPDYI APEVFLQTGY GPACDWWSLG VIMYEMLMGY PPFCSDNPQD TYRKVMNWRE TLIFPPEIPI SEEAKETIIN FCCEADRRLG SQRGLEDLKS VPFFRGVDWE HIRERPAAIP VEVRSIDDTS NFDEFPDVSL EIPSAPIPQG GEIAKDWVFI NYTYKRFEVR NLE
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Serine/threonine-protein kinase involved in controlling cell structure and proliferation of a variety of polarized outgrowths including epidermal hairs, bristles, arista laterals, and dendrites. Together with fry, maintains the integrity of epidermal hairs and is an essential component of the signaling pathway regulating dendritic branching of sensory neurons. Reduces neurite outgrowth by phosphorylating pav, thereby inhibiting its function in microtubule-microtubule sliding.
  • 基因功能参考文献：
    1. Data show that Tricornered Kinase (Trc) regulates the Wiskott-Aldrich syndrome protein (WASP) levels largely, by regulating the transcription of WASP. PMID: 26393506
    2. The regulation of Warts conformation by Mats, Fat/Dachsous signaling, and Dachs appears independent of Warts phosphorylation by Hippo kinase, establishing a precedent for the control of Nuclear Dbf2-related kinases PMID: 26702832
    3. Mutations in trc and wts genes lead to changes in cell shape, cellular levels of F-actin, the timing of differentiation, and the expression of multiple wing hairs and DE-Cadherin. PMID: 20211163
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Protein kinase superfamily, AGC Ser/Thr protein kinase family
  • 组织特异性：
    Expressed in the peripheral and central nervous system (at protein level). Expressed in the wing imaginal disk.
  • 数据库链接：

    KEGG: dme:Dmel_CG8637

    STRING: 7227.FBpp0304464

    UniGene: Dm.2518