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  4. Recombinant Drosophila melanogaster Protein Z600 (Z600)

Recombinant Drosophila melanogaster Protein Z600 (Z600)

  • 货号：
    CSB-YP322166DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP322166DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP322166DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP322166DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP322166DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Z600
  • Uniprot No.：
  • 别名：
    Z600; frs; CG17962; Protein Z600; Protein Fruhstart
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-90
  • 氨基酸序列
    MSSTNETNQV LQRLNSLKIV ETPKEQHEFG KRECYSLDSK KYSLVPATPS SSGHGKFQTE LKKRRKNKLN RMYTYEADKN FIKARKSLNF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Cell cycle regulator that is involved in modulating and adjusting cell proliferation according to the requirements of the developmental program. Interacts with mitotic Cdk1-cyclin complexes to inhibit mitotic entry at the G2/M transition. Likely to function by binding to the hydrophobic patch of cyclins to interfere with the interaction between the complex and certain Cdk1 substrates. At the mid-blastula transition, involved in the cell cycle arrest in G2 of cycle 14 by delaying mitosis and thus reducing cell proliferation allowing cell fate specification and morphogenesis to take place. Acts downstream or in parallel to the checkpoint regulator grp which is also required for the cell cycle pause at cycle 14. During gastrulation, delays mitosis in the ventral region of the embryonic mesoderm thus allowing invagination to be completed before cell division takes place.
  • 基因功能参考文献：
    1. Data show that fruhstart is involved in pausing the cleavage cell cycle in the fertilized egg. PMID: 12919679
    2. Study show that in Drosophila the mitotic inhibitor Fruhstart (Frs) binds specifically and with high affinity to the hydrophobic patch of cyclins. PMID: 17431409
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    KEGG: dme:Dmel_CG17962

    STRING: 7227.FBpp0075304

    UniGene: Dm.24004