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  4. Recombinant Drosophila melanogaster Phosrestin-2 (Arr1)

Recombinant Drosophila melanogaster Phosrestin-2 (Arr1)

  • 货号：
    CSB-YP323620DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP323620DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP323620DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP323620DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP323620DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Arr1
  • Uniprot No.：
  • 别名：
    Arr1; ArrA; CG5711Phosrestin-2; Arrestin-1; Arrestin-A; Phosrestin II
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-364
  • 氨基酸序列
    MVVNFKVFKK CSPNNMITLY MNRRDFVDSV TQVEPIDGII VLDDEYVRQN RKIFVQLVCN FRYGREDDEM IGLRFQKELT LVSQQVCPPQ KQDIQLTKMQ ERLLKKLGSN AYPFVMQMPP SSPASVVLQQ KASDESQPCG VQYFVKIFTG DSDCDRSHRR STINLGIRKV QYAPTKQGIQ PCTVVRKDFL LSPGELELEV TLDKQLYHHG EKISVNICVR NNSNKVVKKI KAMVQQGVDV VLFQNGQFRN TIAFMETSEG CPLNPGSSLQ KVMYLVPTLV ANCDRAGIAV EGDIKRKDTA LASTTLIASQ DARDAFGIIV SYAVKVKLFL GALGGELCAE LPFILMHPKP SRKAQLEAEG SIEA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Regulates photoreceptor cell deactivation. Arr1 and Arr2 proteins are mediators of rhodopsin inactivation and are essential for the termination of the phototransduction cascade.
  • 基因功能参考文献：
    1. Arr1 translocates to rhabdomeres to modulate deactivation of phosphorylated rhodopsin in adult photoreceptors but becomes internalized in pupal photoreceptors. PMID: 24838243
    2. Arr1 mediates an endocytotic cell-survival activity, scavenging phosphorylated rhodopsin and thereby countering toxic Arr2/Rh1 accumulation. PMID: 16213818
  • 蛋白家族：
    Arrestin family
  • 组织特异性：
    Expressed specifically and abundantly in the photoreceptors. Inner and outer segments, and the inner plexiform regions of the retina.
  • 数据库链接：

    KEGG: dme:Dmel_CG5711

    STRING: 7227.FBpp0298351

    UniGene: Dm.450