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  4. Recombinant Drosophila melanogaster Lipid storage droplets surface-binding protein 2 (Lsd-2)

Recombinant Drosophila melanogaster Lipid storage droplets surface-binding protein 2 (Lsd-2)

  • 中文名称：
    黑腹果蝇Lsd-2重组蛋白
  • 货号：
    CSB-YP892915DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇Lsd-2重组蛋白
  • 货号：
    CSB-EP892915DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇Lsd-2重组蛋白
  • 货号：
    CSB-EP892915DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇Lsd-2重组蛋白
  • 货号：
    CSB-BP892915DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇Lsd-2重组蛋白
  • 货号：
    CSB-MP892915DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Lsd-2
  • Uniprot No.：
  • 别名：
    Lsd-2; CG9057; Lipid storage droplets surface-binding protein 2; Lsd2
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-352
  • 氨基酸序列
    MASAEQKHAT GNGTTGNGTA MNDVDQPKDA KDLLPHLESL ERIIKLPVVN AAWDKSQDVY GKVKGKNRVF EWALTAAEDC VTRAVTTAAP FVTKLDRPIA YVDQTLVKGI DKLEVKAPII KDTPQEIYNQ AKSKVIDVVQ PHLERVVKFK AAGQQKAASL KDLAWQKANE VLATQYGSLA VNGVDTTTAL AERLLEYYFP KCESDVEEDN DDKQNAVVQN GKSSENDMPV PASEDPVLHT VQTVGRLSNK ISRRVYRNVS RQIKQVQKGN INDYLSSLIA ALKLHQYINF INSSMGTNVE QSGGSSSDAC SPFGTTTSTT TTTTTSSTSN NKPVVALPHV AKSKRAPAVS SQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Essential for embryogenesis. Required for normal deposition of neutral lipids in the oocyte.
  • 基因功能参考文献：
    1. that HDAC6 is associated physically with the chaperone protein dHsc4/Hsc70 to maintain the proteostasis of PLIN2 PMID: 28966044
    2. Perilipin homologus, LSD2 plays a role in sleep regulation and prevents learning impariment following sleep loss. PMID: 20824166
    3. Lsd2, one of only two PAT domain-encoding genes in the Drosophila genome acts in a Perilipin-like manner, suggesting that components regulating homeostasis of lipid-based energy storage at the lipid droplet membrane are evolutionarily conserved. PMID: 12676093
    4. Lsd2 has an evolutionarily conserved function in lipid metabolism PMID: 14550535
    5. Lsd-2 is expressed and controls lipid storage in wing imaginal discs. PMID: 15704138
    6. LSD2 regulates both lipid metabolism and transport along microtubules in embryos. PMID: 16051169

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  • 亚细胞定位：
    Cytoplasm. Lipid droplet.
  • 蛋白家族：
    Perilipin family
  • 组织特异性：
    Ubiquitous expression in early embryos. At stage 5 expression is restricted to the pole cells. At stage 11 expression is seen in the amnioserosa, refined to the fat body and midgut by stage 14. Also seen in the hindgut by the end of embryogenesis. Express
  • 数据库链接：

    KEGG: dme:Dmel_CG9057

    UniGene: Dm.4079