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  4. Recombinant Drosophila melanogaster Guanine nucleotide-binding protein G (q) subunit alpha

Recombinant Drosophila melanogaster Guanine nucleotide-binding protein G (q) subunit alpha

  • 货号：
    CSB-YP328417DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP328417DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP328417DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP328417DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP328417DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Galphaq
  • Uniprot No.：
  • 别名：
    Galphaq; dgq; dGqalpha; Galpha; Galpha49b; Gq; Gqalpha; CG17759G protein alpha q subunit; Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding protein alpha-q; dGQalpha
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-353
  • 氨基酸序列
    MECCLSEEAK EQKRINQEIE KQLRRDKRDA RRELKLLLLG TGESGKSTFI KQMRIIHGSG YSDEDKRGYI KLVFQNIFMA MQSMIKAMDM LKISYGQGEH SELADLVMSI DYETVTTFED PYLNAIKTLW DDAGIQECYD RRREYQLTDS AKYYLSDLAR IEQADYLPTE QDILRARVPT TGILEYPFDL DGIVFRMVDV GGQRSERRKW IHCFENVTSI IFLVALSEYD QILFESDNEN RMEESKALFR TIITYPWFQN SSVILFLNKK DLLEEKIMYS HLVDYFPEYD GPKQDHAAAK QFVLKKYLAC NPDPERQCYS HFTTATDTEN IKLVFCAVKD TIMQNALKEF NLG
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Could be the transducin analog, an amplifier and one of the transducers of a visual impulse that performs the coupling between opsin and cGMP-phosphodiesterase. Could mediate a subset of olfactory and gustatory responses.
  • 基因功能参考文献：
    1. A single residue mutation in the G-Protein, Gq, causes blindness in Drosophila. PMID: 29158337
    2. Gq modulates termination of phototransduction and prevents retinal degeneration PMID: 22389492
    3. demonstrated that light causes massive and reversible translocation of the visual Gqalpha to the cytosol, associated with marked architectural changes in the photoreceptors PMID: 12554647
    4. Data suggest that prolonged G(q) activity triggers rhodopsin endocytosis and degradation, and reduces photoreceptor sensitivity in Drosophila. PMID: 18034157
    5. Reduced odor responses from antennal neurons of G(q)alpha mutants in Drosophila support a role for a phospholipid intermediate in insect olfactory transduction. PMID: 18448651

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  • 蛋白家族：
    G-alpha family, G(q) subfamily
  • 组织特异性：
    Isoform D is expressed only in the retina and ocellus of the adult head. Isoform A is expressed in chemosensory cells of the olfactory and taste structures, including a subset of olfactory and gustatory neurons, and in cells of the central nervous system,
  • 数据库链接：

    KEGG: dme:Dmel_CG17759

    UniGene: Dm.13902