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  4. Recombinant Drosophila melanogaster Flightin (fln)

Recombinant Drosophila melanogaster Flightin (fln)

  • 货号：
    CSB-YP327427DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP327427DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP327427DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP327427DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP327427DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    fln
  • Uniprot No.：
  • 别名：
    fln; FTN; mp27; CG7445Flightin; Muscle protein 27
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-182
  • 氨基酸序列
    MADEEDPWGF DDGGEEEKAA STQAGTPAPP SKAPSVASDH KADSVVAGTP ANEEAAPEEV EEIKAPPPPP EDDGYRKPVQ LYRHWVRPKF LQYKYMYNYR TNYYDDVIDY IDKKQTGVAR EIPRPQTWAE RVLRTRNISG SDIDSYAPAK RDKQLIQTLA ASIRTYNYHT KAYINQRYAS VL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Possibly involved in the regulation of flight muscles contraction, possibly by modulating actin-myosin interaction.
  • 基因功能参考文献：
    1. phosphorylation of D. melanogaster flightin is modulated during flight PMID: 26691840
    2. COOH terminus of flightin is necessary for normal myofilament lattice organization, thereby facilitating the cross-bridge binding required to achieve high power output for flight. PMID: 21593450
    3. used atomic force microscopy to study the morphological and mechanical properties of fully hydrated native thick filaments isolated from indirect flight muscle of normal and mutants lacking flightin PMID: 19917296
    4. Flightin is a major contributor to myofilament stiffness and a key determinant of the enhanced delayed force response to stretch in Drosophila flight muscles. PMID: 12954604
    5. Results illustrate the importance of flightin in flight muscle development and function. PMID: 15671343
    6. Myofilin is probably needed for filament assembly in all muscles, and flightin for stability of flight muscle thick filaments in adult flies PMID: 15769842

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  • 组织特异性：
    Found only in indirect flight muscles (IFM).
  • 数据库链接：

    KEGG: dme:Dmel_CG7445

    STRING: 7227.FBpp0074679

    UniGene: Dm.2517