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  4. Recombinant Drosophila grimshawi Protein maelstrom (mael)

Recombinant Drosophila grimshawi Protein maelstrom (mael)

  • 中文名称：
    Recombinant Drosophila grimshawi Protein maelstrom(mael),Yeast
  • 货号：
    CSB-YP451851DLL
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Drosophila grimshawi Protein maelstrom(mael),Yeast
  • 货号：
    CSB-EP451851DLL
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Drosophila grimshawi Protein maelstrom(mael),Yeast
  • 货号：
    CSB-EP451851DLL-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Drosophila grimshawi Protein maelstrom(mael),Yeast
  • 货号：
    CSB-BP451851DLL
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Drosophila grimshawi Protein maelstrom(mael),Yeast
  • 货号：
    CSB-MP451851DLL
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    mael
  • Uniprot No.：
  • 别名：
    mael; GH14807Protein maelstrom
  • 种属：
    Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-429
  • 氨基酸序列
    MAPKKTNGFM IFVNEWRKGR NISIAQAVSH CGDIWKNMSA QQKGPYNGFA KDANVSARAK VEPLDCHGRP LSAVERENCE AAEREMNMKR NIERIVLEGK AQHDLENTKF IFAAFNYFTK AIGNDIYMPA EFAACKFSLR SGRGPVYSSH INPGQLIFGQ ASDAQHHTST THQLPLPPKA MGESNMGSLY VNIVKYLRDC QGAGNPLVVF TTAELMPVVS GCFRYLQSDS DEVGEQIHVY DILYLFYVLK KEVMDIADLP HANINKCITD NFFFNDFFEY YSNIACQFHE DNDRGKYCTH SMVSRWCYTF CDYMCGDLAI KPLAGKHMPP VQEQKFCVTN PDKSMCGNTS YNSVSSWHSD VKQEPDSDYT PEDHSVFSAN LTATEEFPSL SGRRPKPTHR HPPPQKGAWN VPAAKRSARD FDDAFNMTR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved both in the piRNA and miRNA metabolic processes. As a component of the meiotic nuage, plays a central role during oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Repression of transposable elements is mediated via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the repression of transposons. As a nuclear component, it is required for proper differentiation in the germline stem cell (GSC) lineage by repressing microRNA-7 (miR-7), thereby acting as an indirect regulator of bag-of-marbles (Bam). Acts by binding to the promoter of miR-7 gene and repressing its expression; miR-7 repression alleviates the Bam repression by miR-7, thereby allowing differentiation in the germline stem cell (GSC) lineage.
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Maelstrom family
  • 数据库链接：

    KEGG: dgr:Dgri_GH14807

    STRING: 7222.FBpp0148713