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  4. Recombinant Dictyostelium discoideum Autocrine proliferation repressor protein A (aprA)

Recombinant Dictyostelium discoideum Autocrine proliferation repressor protein A (aprA)

  • 中文名称：
    Recombinant Dictyostelium discoideum Autocrine proliferation repressor protein A(aprA),Yeast
  • 货号：
    CSB-YP726391DKK
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Dictyostelium discoideum Autocrine proliferation repressor protein A(aprA),Yeast
  • 货号：
    CSB-EP726391DKK
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Dictyostelium discoideum Autocrine proliferation repressor protein A(aprA),Yeast
  • 货号：
    CSB-EP726391DKK-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Dictyostelium discoideum Autocrine proliferation repressor protein A(aprA),Yeast
  • 货号：
    CSB-BP726391DKK
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Dictyostelium discoideum Autocrine proliferation repressor protein A(aprA),Yeast
  • 货号：
    CSB-MP726391DKK
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    aprA
  • Uniprot No.：
  • 别名：
    aprA; DDB_G0281663Autocrine proliferation repressor protein A; PhoPQ-activated pathogenicity-related protein
  • 种属：
    Dictyostelium discoideum (Slime mold)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    19-494
  • 氨基酸序列
    TP LDDYVNAPDD TYKWTLNNTI EYETFTGYIL ELTSQTWMAE KSDWPVWKHW VSICVPKGVT TTTTFIYVDG GSNDNWKVPG SMDQTIEIVC LSSGSVSVGL TQIPNQPIIF NNDGVQRFED DLVAYTWRQF LGNTSEPLWL ARLPMTKAVV KCMDAVQEFG KTIGYNSENF VIAGASKRGW TTWLAGVVDP RIIAIVPIVM PILNMIPNMG HQFYAYGEWS FALNDYTGQG VMDYLNGPQM VELAAIVDPF SYRDRYTMPI YAIASSDDEF FLPDSPQFFW NNLTATPEKH LRIVPNAEHS LMGHQIDIIL SIVTFVRLLI TNQPRPTFTW DITYSEDLNS GTIVLTVPEG GIIPYKVKVW TAVTESTTRR DFRIITCMDI TKCIQFIIWD PSDITPTSTG VYSITLSKPD AGWRAFFLEA EYLYAKNSID DEYTLKFTSE VAIVPNTLPF GSCSEYNACG DGSQGDSASS TATL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Inhibitor that slows proliferation of secreting cells (also known as chalone). May function by binding to cell surface receptors. Requires cfaD for activity. Overexpression slows proliferation.
  • 基因功能参考文献：
    1. like AprA, DPPIV is a chemorepellent for, and inhibits the proliferation of, D. discoideum cells, and that AprA binds some DPPIV binding partners such as fibronectin. PMID: 28028841
    2. Our data indicate that the endogenous signal AprA acts as an autocrine chemorepellant for Dictyostelium cells. PMID: 22711818
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    PqaA family
  • 数据库链接：

    KEGG: ddi:DDB_G0281663

    STRING: 44689.DDB0231036