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  4. Recombinant Chicken Methyltransferase-like protein 14 (METTL14)

Recombinant Chicken Methyltransferase-like protein 14 (METTL14)

  • 中文名称：
    鸡METTL14重组蛋白
  • 货号：
    CSB-YP726511CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    鸡METTL14重组蛋白
  • 货号：
    CSB-EP726511CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    鸡METTL14重组蛋白
  • 货号：
    CSB-EP726511CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    鸡METTL14重组蛋白
  • 货号：
    CSB-BP726511CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    鸡METTL14重组蛋白
  • 货号：
    CSB-MP726511CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    METTL14; RCJMB04_13h15; N6-adenosine-methyltransferase non-catalytic subunit; Methyltransferase-like protein 14
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-459
  • 氨基酸序列
    MNSRLQEIRE RQKLRRQLLA QQLGAENADS IGAVLNSKDD QREIAETRET CRASYDTSAP NAKRKYPDEG EADEEEIEEY KDEVELQQDE ENLPYEEEIY KDSSTFLKGT QSLNPHNDYC QHFVDTGHRP QNFIRDVGLA DRFEEYPKLR ELIRLKDELI SKSNTPPMYL QADLEAFDIR ELKSKFDVIL LEPPLEEYYR ETGITANEKC WTWDDIMKLE IEEIAAPRSF VFLWCGSGEG LDLGRVCLRK WGYRRCEDIC WIKTNKNNPG KTKTLDPKAV FQRTKEHCLM GIKGTVRRST DGDFIHANVD IDLIITEEPE IGNIEKPVEI FHIIEHFCLG RRRLHLFGRD STIRPGWLTV GPTLTNSNFN AETYSSYFTA PNSHLTGCTE EIERLRPKSP PPKSKSDRGG GAPRGGGRGG TSAGRGERGR ERNRTNFRGE RGGFRGGRGG THRGGFPTR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with METTL3, METTL14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing.
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    MT-A70-like family
  • 数据库链接：

    KEGG: gga:422684

    STRING: 9031.ENSGALP00000019558

    UniGene: Gga.2891