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  4. Recombinant Bovine Somatostatin (SST)

Recombinant Bovine Somatostatin (SST)

  • 中文名称：
    牛SST重组蛋白
  • 货号：
    CSB-YP022723BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    牛SST重组蛋白
  • 货号：
    CSB-EP022723BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    牛SST重组蛋白
  • 货号：
    CSB-EP022723BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    牛SST重组蛋白
  • 货号：
    CSB-BP022723BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    牛SST重组蛋白
  • 货号：
    CSB-MP022723BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SST
  • Uniprot No.：
  • 别名：
    SST; Somatostatin [Cleaved into: Somatostatin-28; Somatostatin-14; Neuronostatin; NST)]
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Cytoplasmic domain
  • 表达区域：
    89-116
  • 氨基酸序列
    SA NSNPAMAPRE RKAGCKNFFW KTFTSC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH-stimulated secretion of GH1 and LH; the inhibition of ghrelin-stimulated secretion of GH1 can be further increased by neuronostatin.; May enhance low-glucose-induced glucagon release by pancreatic alpha cells. This effect may be mediated by binding to GPR107 and PKA activation. May regulate cardiac contractile function. May compromise cardiomyocyte viability. In the central nervous system, may impair memory retention and may affect hippocampal excitability. May also have anxiolytic and anorexigenic effects. May play a role in arterial pressure regulation. May inhibit basal, but not ghrelin- or GnRH-stimulated secretion of GH1 or LH, but does not affect the release of other pituitary hormones, including PRL, ACTH, FSH or TSH. Potentiates inhibitory action of somatostatin on ghrelin-stimulated secretion of GH1, but not that on GnRH-stimulated secretion of LH.
  • 基因功能参考文献：
    1. Individuals with genotype AA of somatostatin had significantly lower body height, body length, hip width, and hucklebone width values compared to AG at 1.5 years old PMID: 21523659
    2. The present study, provides evidence of pro-SST and SST receptor (SSTR1 and 2A) mRNA expression in ocular ciliary epithelium (CE). PMID: 16764985
    3. The distribution and morphology of neurons containing somatostatin (SOM) was investigated in the amygdala (CA) of the pig. PMID: 18519243
    4. Data show that PKA and PKC pathways are involved in the differential regulation of production of the neuropeptides (Met)enkephalin, galanin, somatostatin, NPY, and VIP. PMID: 18619673
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Somatostatin family
  • 数据库链接：

    KEGG: bta:280932

    STRING: 9913.ENSBTAP00000023020

    UniGene: Bt.49664