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  4. Recombinant Bovine Sigma non-opioid intracellular receptor 1 (SIGMAR1), partial

Recombinant Bovine Sigma non-opioid intracellular receptor 1 (SIGMAR1), partial

  • 中文名称：
    牛SIGMAR1重组蛋白
  • 货号：
    CSB-YP021320BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    牛SIGMAR1重组蛋白
  • 货号：
    CSB-EP021320BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    牛SIGMAR1重组蛋白
  • 货号：
    CSB-EP021320BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    牛SIGMAR1重组蛋白
  • 货号：
    CSB-BP021320BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    牛SIGMAR1重组蛋白
  • 货号：
    CSB-MP021320BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    SIGMAR1; OPRS1; Sigma non-opioid intracellular receptor 1; Sigma 1-type opioid receptor; Sigma1-receptor; Sigma1R
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration. Necessary for proper mitochondrial axonal transport in motor neurons, in particular the retrograde movement of mitochondria. Plays a role in protecting cells against oxidative stress-induced cell death via its interaction with RNF112.
  • 基因功能参考文献：
    1. Sig1R through Rac1 signaling induces mild oxidative stress that possibly is involved in the regulation of neuroplasticity PMID: 25924612
  • 亚细胞定位：
    Nucleus inner membrane. Nucleus outer membrane. Nucleus envelope. Cytoplasmic vesicle. Endoplasmic reticulum membrane. Membrane; Single-pass membrane protein. Lipid droplet. Cell junction. Cell membrane. Cell projection, growth cone. Cell junction, synapse, postsynaptic density membrane.
  • 蛋白家族：
    ERG2 family
  • 数据库链接：

    KEGG: bta:538903

    STRING: 9913.ENSBTAP00000020990

    UniGene: Bt.714