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  4. Recombinant Bovine Pleckstrin homology domain-containing family O member 1 (PLEKHO1)

Recombinant Bovine Pleckstrin homology domain-containing family O member 1 (PLEKHO1)

  • 中文名称：
    牛PLEKHO1重组蛋白
  • 货号：
    CSB-YP018186BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    牛PLEKHO1重组蛋白
  • 货号：
    CSB-EP018186BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    牛PLEKHO1重组蛋白
  • 货号：
    CSB-EP018186BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    牛PLEKHO1重组蛋白
  • 货号：
    CSB-BP018186BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    牛PLEKHO1重组蛋白
  • 货号：
    CSB-MP018186BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PLEKHO1
  • Uniprot No.：
  • 别名：
    PLEKHO1; Pleckstrin homology domain-containing family O member 1; PH domain-containing family O member 1
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-409
  • 氨基酸序列
    MMKKNNSTKR GPQDGNHQCA PPEKVGWVRK FCGKGIFREI WKNRYVVLKG DQLYISEKEV KDEKNIQEVF DLSDYEKCEE LRKSKSRSKK NHSKFTLAHS KQPGNTAPNL IFLAVSPEEK ESWINALNSA ITRAKNRVLD EVTVEEDSYL AHPTRDRAKI QHSRRPPTRG HLMAVASTST SDGMLTLDLI QEEDPSPEEP TSCAESFRVD LDKSVAQLAG SRRRADSDRI QPSSDRASGL PRLWEKPDKG ATYTPQAPKK LTATEKSRCA SLEEILSQRD AVPAHTLQRR AEDPPTPIPH APGQLSRIQD LVARKLEKTQ ELLAEVQGLG DGKRKAKEPP RSPPDSESEQ LLLETERLLG EASSNWSQAK RVLQEVRELR DLYRQMDLQT PDSHLRQTTQ HSQYRKSLM
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.
  • 亚细胞定位：
    Membrane. Nucleus. Cytoplasm.
  • 数据库链接：

    KEGG: bta:788251

    STRING: 9913.ENSBTAP00000006381

    UniGene: Bt.20245