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  4. Recombinant Bovine Hyaluronidase-2 (HYAL2)

Recombinant Bovine Hyaluronidase-2 (HYAL2)

  • 中文名称：
    牛HYAL2重组蛋白
  • 货号：
    CSB-YP837340BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    牛HYAL2重组蛋白
  • 货号：
    CSB-EP837340BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    牛HYAL2重组蛋白
  • 货号：
    CSB-EP837340BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    牛HYAL2重组蛋白
  • 货号：
    CSB-BP837340BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    牛HYAL2重组蛋白
  • 货号：
    CSB-MP837340BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    HYAL2
  • Uniprot No.：
  • 别名：
    HYAL2; Hyaluronidase-2; Hyal-2; EC 3.2.1.35; Hyaluronoglucosaminidase-2
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    full length protein
  • 表达区域：
    21-451
  • 氨基酸序列
    TELKPTAPPI FTGRPFVVAW DVPTQDCGPR HKMPLDPKDM KAFDVQASPN EGFVNQNITI FYRDRLGMYP HFNSVGRSVH GGVPQNGSLW VHLEMLKGHV EHYIRTQEPA GLAVIDWEDW RPVWVRNWQD KDVYRRLSRH LVAIRHPDWP PERVAKEAQY EFEFAARQFM LETLRFVKAF RPRHLWGFYL FPDCYNHDYV QNWETYTGRC PDVEVSRNDQ LAWLWAESTA LFPSVYLEET LASSTHGRNF VSFRVQEALR VADVHHANHA LPVYVFTRPT YSRGLTGLSE MDLISTIGES AALGAAGVIL WGDAGFTTSN ETCRRLKDYL TRSLVPYVVN VSWAAQYCSW AQCHGHGRCV RRDPNAHTFL HLSASSFRLV PSHAPDEPRL RPEGELSWAD RNHLQMHFRC QCYLGWGGEQ CQWDRRRAAG G
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R.
  • 基因功能参考文献：
    1. CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2. PMID: 25864644
    2. HYAL2 expression improves the blastocyst rate and embryo quality, an effect which requires CD44 activity and MAPK signaling. PMID: 23625939
    3. May degrade hyaluronan by analogy to human HYAL2, which is a weak acid-active hyaluronidase. Serves as an entry receptor for jaagsiekte sheep retrovirus in sheep and bovine as well as for enzootic nasal tumor virus in sheep. PMID: 11836391
  • 亚细胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族：
    Glycosyl hydrolase 56 family
  • 数据库链接：

    KEGG: bta:281838

    STRING: 9913.ENSBTAP00000000612

    UniGene: Bt.29683