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  4. Recombinant Arabidopsis thaliana Transcription factor DYSFUNCTIONAL TAPETUM 1 (DYT1)

Recombinant Arabidopsis thaliana Transcription factor DYSFUNCTIONAL TAPETUM 1 (DYT1)

  • 中文名称：
    拟南芥DYT1重组蛋白
  • 货号：
    CSB-YP530539DOA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    拟南芥DYT1重组蛋白
  • 货号：
    CSB-EP530539DOA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    拟南芥DYT1重组蛋白
  • 货号：
    CSB-EP530539DOA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    拟南芥DYT1重组蛋白
  • 货号：
    CSB-BP530539DOA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    拟南芥DYT1重组蛋白
  • 货号：
    CSB-MP530539DOA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DYT1
  • Uniprot No.：
  • 别名：
    DYT1; BHLH22; EN49; At4g21330; T6K22.60Transcription factor DYT1; Basic helix-loop-helix protein 22; AtbHLH22; bHLH 22; Protein DYSFUNCTIONAL TAPETUM 1; Transcription factor EN 49; bHLH transcription factor bHLH022
  • 种属：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-207
  • 氨基酸序列
    MGGGSRFQEP VRMSRRKQVT KEKEEDENFK SPNLEAERRR REKLHCRLMA LRSHVPIVTN MTKASIVEDA ITYIGELQNN VKNLLETFHE MEEAPPEIDE EQTDPMIKPE VETSDLNEEM KKLGIEENVQ LCKIGERKFW LKIITEKRDG IFTKFMEVMR FLGFEIIDIS LTTSNGAILI SASVQTQELC DVEQTKDFLL EVMRSNP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription factor. Involved in the control of tapetum development. Required for male fertility and pollen differentiation, especially during callose deposition.
  • 基因功能参考文献：
    1. Early onset torsion dystonia (DYT1) patient fibroblasts with heterozygous DYT1 mutant alleles showed decreased herpes simplex virus 1 plaque formation as compared to controls. PMID: 29396398
    2. DYT1 dystonia is a network disorder, with crucial nodes in sensory-motor integration of posterior parietal structures. PMID: 27453152
    3. The results of this study suggested that motor impairments in DYT1 KI animals only exhibit when the sensory stimuli are strongly altered during performance. PMID: 27769743
    4. Data said that the normal spatio-temporal subcellular localization of DYT1 is important for DYT1 function and/or that the BIF domains from different bHLH members might be functionally distinct. PMID: 27113773
    5. Here the s demonstrate abnormal risk taking in DYT1 dystonia patients, which is correlated with disease severity, thereby supporting striatal plasticity in shaping choice behavior in humans. PMID: 27249418
    6. we show the behavioral and molecular consequences of stressing the endoplasmic reticulum in DYT1 mice by increasing the amount of misfolded proteins PMID: 27707963
    7. DYT1 forms complexes with bHLH010, bHLH089 and bHLH091 subsequently affecting the correct expression of many DYT1 target genes. PMID: 26216374
    8. DYT1 positively regulates genes for lipid metabolism, cell-wall modification and secondary metabolism that are important for pollen development. PMID: 22775442
    9. DYT1 encodes a putative bHLH transcription factor and is a component of a genetic network that controls anther development and function. [DYT1] PMID: 16831835

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  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Mostly expressed in anthers, and, to a lower extent, in young inflorescences undergoing meiosis and siliques.
  • 数据库链接：

    KEGG: ath:AT4G21330

    STRING: 3702.AT4G21330.1

    UniGene: At.54456