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  4. Recombinant Arabidopsis thaliana Meiotic recombination protein DMC1 homolog (LIM15)

Recombinant Arabidopsis thaliana Meiotic recombination protein DMC1 homolog (LIM15)

  • 中文名称：
    拟南芥DMC1重组蛋白
  • 货号：
    CSB-YP657183DOA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    拟南芥DMC1重组蛋白
  • 货号：
    CSB-EP657183DOA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    拟南芥DMC1重组蛋白
  • 货号：
    CSB-EP657183DOA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    拟南芥DMC1重组蛋白
  • 货号：
    CSB-BP657183DOA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    拟南芥DMC1重组蛋白
  • 货号：
    CSB-MP657183DOA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DMC1
  • Uniprot No.：
  • 别名：
    DMC1; LIM15; At3g22880; F5N5.6Meiotic recombination protein DMC1 homolog; AtDMC1
  • 种属：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-344
  • 氨基酸序列
    MMASLKAEET SQMQLVEREE NDEDEDLFEM IDKLIAQGIN AGDVKKLQEA GIHTCNGLMM HTKKNLTGIK GLSEAKVDKI CEAAEKIVNF GYMTGSDALI KRKSVVKITT GCQALDDLLG GGIETSAITE AFGEFRSGKT QLAHTLCVTT QLPTNMKGGN GKVAYIDTEG TFRPDRIVPI AERFGMDPGA VLDNIIYARA YTYEHQYNLL LGLAAKMSEE PFRILIVDSI IALFRVDFTG RGELADRQQK LAQMLSRLIK IAEEFNVAVY MTNQVIADPG GGMFISDPKK PAGGHVLAHA ATIRLLFRKG KGDTRVCKVY DAPNLAEAEA SFQITQGGIA DAKD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks. Mediates interhomolog recombination during meiosis.
  • 基因功能参考文献：
    1. KLU is required for normal DMC1 expression pattern in ovules undergoing megasporogenesis. PMID: 25182975
    2. The DMC1 siRNA interfered with meiotic progression and, consequently, the flowers were at least partially sterile. PMID: 25039964
    3. Our data demonstrate that RAD51 plays a supporting role for DMC1 in meiotic recombination in the flowering plant, Arabidopsis. PMID: 24086145
    4. Results demonstrate that DMC1 functions independently and spatially separated from RAD51 during meiosis and that ATR is an integral part of the regular meiotic program. PMID: 22589466
    5. Establishment and stabilisation of pairing of homologous centromeric and pericentromeric regions depends principally upon DMC1, while pairing and synapsis of euchromatic chromosome arms of homologues requires the presence of RAD51 . PMID: 22532804
    6. AtRAD51 may be required to ensure the fidelity of homologous recombination in the interchromosomal exchanges initiated by AtDMC1. PMID: 22066484
    7. AtBRCA2 is required for proper meiotic synapsis and mediates the recruitment of AtRAD51 and AtDMC1. PMID: 22077663

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    RecA family, DMC1 subfamily
  • 组织特异性：
    Expressed in mitotic and/or meiotic tissues. Expressed in roots, leaves and anthers and carpels of young fower buds.
  • 数据库链接：

    KEGG: ath:AT3G22880

    STRING: 3702.AT3G22880.1

    UniGene: At.50216