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Recombinant Anemonia sulcata Delta-actitoxin-Avd1c

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  • 中文名称：
    Recombinant Anemonia sulcata Delta-actitoxin-Avd1c
  • 货号：
    CSB-YP355673AKE
  • 规格：
    ￥2616
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP355673AKE could indicate that this peptide derived from Yeast-expressed Anemonia sulcata (Mediterranean snakelocks sea anemone) Delta-actitoxin-Avd1c.
    • Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP355673AKE could indicate that this peptide derived from Yeast-expressed Anemonia sulcata (Mediterranean snakelocks sea anemone) Delta-actitoxin-Avd1c.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    N/A
  • Uniprot No.：
  • 别名：
    Delta-actitoxin-Avd1c; Delta-AITX-Avd1c; ATX-II; ATX II; Anemonia sulcata toxin 2; As2; Neurotoxin 2; Toxin II
  • 种属：
    Anemonia sulcata (Mediterranean snakelocks sea anemone)
  • 蛋白长度：
    Full Length
  • 来源：
    Yeast
  • 分子量：
    6.9kDa
  • 表达区域：
    1-47aa
  • 氨基酸序列
    GVPCLCDSDGPSVRGNTLSGIIWLAGCPSGWHNCKKHGPTIGWCCKQ
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 6xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Binds specifically to voltage-gated sodium channels (Nav) (site 3), thereby delaying their inactivation. Has a strong effect on crustaceans and insects (DmNav1) and a weaker effect on mammals. This toxin is highly potent at mammalian Nav1.1/SCN1A (EC(50)=6.01 nM) and Nav1.2/SCN2A (EC(50)=7.88 nM). It has also great activity on Nav1.5/SCN5A (EC(50)=49.05 nM), Nav1.4/SCN4A (EC(50)=109.49 nM) and Nav1.6/SCN8A (EC(50)=about 180 nM) and is less potent on Nav1.3/SCN3A (EC(50)=759.22 nM) (when measured as the increase in the slow component).
  • 亚细胞定位：
    Secreted. Nematocyst.
  • 蛋白家族：
    Sea anemone sodium channel inhibitory toxin family, Type I subfamily