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VPS72 Antibody

  • 中文名称：
    VPS72兔多克隆抗体
  • 货号：
    CSB-PA050222
  • 规格：
    ￥880
  • 图片：
    • Western blot analysis of 293T lysis using VPS72 antibody.
  • 其他：

产品详情

  • Uniprot No.：
    Q15906
  • 基因名：
    VPS72
  • 别名：
    CFL1 antibody; HGNC11644 antibody; Protein YL-1 antibody; Swc2 antibody; TCFL1 antibody; Transcription factor like 1 (YL1) antibody; Transcription Factor Like 1 antibody; Transcription factor-like 1 antibody; Vacuolar protein sorting 72 (yeast) antibody; Vacuolar protein sorting 72 homolog (S. cerevisiae) antibody; Vacuolar protein sorting associated protein 72 homolog antibody; Vacuolar protein sorting-associated protein 72 homolog antibody; VPS72 antibody; VPS72_HUMAN antibody; YL-1 antibody; YL1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human VPS72.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.
  • 基因功能参考文献：
    1. The 2.7-A-resolution crystal structure of the human YL1-H2A.Z-H2B complex shows that YL1 binding, similarly to ANP32E binding, triggers an extension of the H2A.Z alphaC helix. PMID: 26974126
    2. Results identify YL1 as a subunit of the TRRAP/TIP60 HAT complex, and also as a component of a novel mammalian multiprotein complex that includes the SNF2-related helicase SRCAP. PMID: 15647280
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    VPS72/YL1 family
  • 数据库链接：

    HGNC: 11644

    OMIM: 600607

    KEGG: hsa:6944

    STRING: 9606.ENSP00000357887

    UniGene: Hs.2430