SPACA3 Antibody
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中文名称:SPACA3多克隆抗体
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货号:CSB-PA022454GA01HU
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规格:¥3,900
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其他:
产品详情
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Uniprot No.:Q8IXA5
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基因名:SPACA3
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别名:SPACA3 antibody; LYC3 antibody; LYZL3 antibody; SLLP1 antibody; SPRASA antibody; UNQ424/PRO862Sperm acrosome membrane-associated protein 3 antibody; Cancer/testis antigen 54 antibody; CT54 antibody; Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17 antibody; Lysozyme-like protein 3 antibody; Sperm lysozyme-like protein 1 antibody; Sperm protein reactive with antisperm antibodies antibody; Sperm protein reactive with ASA) [Cleaved into: Sperm acrosome membrane-associated protein 3 antibody; membrane form; Sperm acrosome membrane-associated protein 3 antibody; processed form] antibody
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宿主:Rabbit
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反应种属:Human,Mouse,Rat
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免疫原:Human SPACA3
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免疫原种属:Homo sapiens (Human)
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抗体亚型:IgG
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纯化方式:Antigen Affinity purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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产品提供形式:Liquid
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应用范围:ELISA,WB
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.
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基因功能参考文献:
- The levels of antibodies reactive with SPRASA were elevated in infertile women. PMID: 25038051
- SLLP1 represents a promising target for the immunotherapy of multiple myeloma. PMID: 26088750
- s present evidence that the variants could affect the expression levels or function of SPRASA, thereby affecting a couple's fertility. PMID: 24872021
- SLLP1 could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane PMID: 12606493
- SLLP1 is capable of eliciting B-cell immune responses in vivo in cancer-bearing individuals. PMID: 15475442
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亚细胞定位:[Isoform 1]: Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type II membrane protein.; [Isoform 2]: Secreted.
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蛋白家族:Glycosyl hydrolase 22 family
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组织特异性:The processed form is expressed in sperm (at protein level). Expressed in testis, epididymis and placenta.
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数据库链接:
HGNC: 16260
OMIM: 612749
KEGG: hsa:124912
STRING: 9606.ENSP00000269053
UniGene: Hs.434112
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