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SPACA3 Antibody

  • 中文名称:
    SPACA3多克隆抗体
  • 货号:
    CSB-PA022454GA01HU
  • 规格:
    ¥3,900
  • 其他:

产品详情

  • Uniprot No.:
    Q8IXA5
  • 基因名:
    SPACA3
  • 别名:
    SPACA3 antibody; LYC3 antibody; LYZL3 antibody; SLLP1 antibody; SPRASA antibody; UNQ424/PRO862Sperm acrosome membrane-associated protein 3 antibody; Cancer/testis antigen 54 antibody; CT54 antibody; Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17 antibody; Lysozyme-like protein 3 antibody; Sperm lysozyme-like protein 1 antibody; Sperm protein reactive with antisperm antibodies antibody; Sperm protein reactive with ASA) [Cleaved into: Sperm acrosome membrane-associated protein 3 antibody; membrane form; Sperm acrosome membrane-associated protein 3 antibody; processed form] antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human,Mouse,Rat
  • 免疫原:
    Human SPACA3
  • 免疫原种属:
    Homo sapiens (Human)
  • 抗体亚型:
    IgG
  • 纯化方式:
    Antigen Affinity purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA,WB
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.
  • 基因功能参考文献:
    1. The levels of antibodies reactive with SPRASA were elevated in infertile women. PMID: 25038051
    2. SLLP1 represents a promising target for the immunotherapy of multiple myeloma. PMID: 26088750
    3. s present evidence that the variants could affect the expression levels or function of SPRASA, thereby affecting a couple's fertility. PMID: 24872021
    4. SLLP1 could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane PMID: 12606493
    5. SLLP1 is capable of eliciting B-cell immune responses in vivo in cancer-bearing individuals. PMID: 15475442

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  • 亚细胞定位:
    [Isoform 1]: Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type II membrane protein.; [Isoform 2]: Secreted.
  • 蛋白家族:
    Glycosyl hydrolase 22 family
  • 组织特异性:
    The processed form is expressed in sperm (at protein level). Expressed in testis, epididymis and placenta.
  • 数据库链接:

    HGNC: 16260

    OMIM: 612749

    KEGG: hsa:124912

    STRING: 9606.ENSP00000269053

    UniGene: Hs.434112