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ANXA13 Antibody

  • 中文名称：
    ANXA13兔多克隆抗体
  • 货号：
    CSB-PA558622
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA558622(ANXA13 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA558622(ANXA13 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 60 μg, Lane: Mouse small intestine tissue, Primary antibody: CSB-PA558622(ANXA13 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
  • 其他：

产品详情

  • Uniprot No.：
    P27216
  • 基因名：
    ANXA13
  • 别名：
    Annexin A13 antibody; Annexin XIII antibody; Annexin; intestine-specific antibody; Annexin-13 antibody; ANX 13 antibody; ANX A13 antibody; ANX13 antibody; ANX13_HUMAN antibody; ANXA13 antibody; Intestine Specific Annexin antibody; Intestine-specific annexin antibody; ISA antibody; MGC150460 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human ANXA13
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:15-1:50
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner. Half-maximal membrane binding requires about 60 uM calcium. Does not bind to membranes that lack phospholipids with an acidic headgroup.; Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner, but requires higher calcium levels for membrane binding than isoform A. Half-maximal membrane binding requires about 320 uM calcium.
  • 基因功能参考文献：
    1. ANXA13 is associated with colorectal cancer cell invasion in vitro, and with lymph node metastasis and poor survival in colorectal cancer patients PMID: 28423508
    2. High ANXA13 expression is associated with Refractory Lupus Nephritis. PMID: 26110394
    3. Ectopic overexpression of Annexin A13 was likewise sufficient to sensitize malignant breast cancer cells to treatment with Rapamycin. PMID: 20701074
    4. The unique, conserved aspects of annexin A13 primary structure, gene organization, and genetic maps identify it as the probable common ancestor of all vertebrate annexins. PMID: 11961095
  • 亚细胞定位：
    Apical cell membrane. Cell membrane; Lipid-anchor. Cytoplasmic vesicle.
  • 蛋白家族：
    Annexin family
  • 组织特异性：
    Detected in epithelial cells in colon and jejunum (at protein level). Detected in epithelial cells in jejunum.
  • 数据库链接：

    HGNC: 536

    OMIM: 602573

    KEGG: hsa:312

    STRING: 9606.ENSP00000262219

    UniGene: Hs.181107