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  4. Recombinant Mouse Probable E3 ubiquitin-protein ligase makorin-3 (Mkrn3)

Recombinant Mouse Probable E3 ubiquitin-protein ligase makorin-3 (Mkrn3)

  • 中文名称：
    小鼠Mkrn3重组蛋白
  • 货号：
    CSB-YP736743MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Mkrn3重组蛋白
  • 货号：
    CSB-EP736743MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Mkrn3重组蛋白
  • 货号：
    CSB-EP736743MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Mkrn3重组蛋白
  • 货号：
    CSB-BP736743MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Mkrn3重组蛋白
  • 货号：
    CSB-MP736743MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Mkrn3
  • Uniprot No.：
  • 别名：
    Mkrn3; Zfp127; Znf127; Probable E3 ubiquitin-protein ligase makorin-3; EC 2.3.2.27; RING-type E3 ubiquitin transferase makorin-3; Zinc finger protein 127
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-544
  • 氨基酸序列
    MEESTAPIEA HAAAGAEAGA EGGEGVSVPP PPQFEAAGAS AGVSSAPLQQ ASGLAPLLVT PGPAIRRAAS LRPAPAEGGG ARSGPERNSG SWTKQILCRY YLHGQCKEGD NCRYSHDLSG RRRSRGGQDA QPRASADRGP KMATRWEPPT QEVAEAPPAA SSSSLPLIGS AAERGFTEAE IDNAGIRSAA ERGFSEAEID NASLAAGAAA GAGAEGWEGA IEFVPGQPYR GRMVPPHGPE APLQSPAIER EHMAMGMGMP MPVPMPMPVP MPVPMPLPLC RYAARGQCLR GDRCAYPHGE ICDMCGQQAL HPWDAAQQEA HRRACVEAHE RDMELSFAVQ RSMDKVCGIC MEVVYEKADP SDRRFGILFS CNHTYCLRCI RRWRSATQFE NRISKSCPQC RVSSGFVIPS EFWVEEEEEK EKLVQQYKEG MSQKACRYFA GGLGHCPFGE FCFYKHEYPE GWRDQPPRPD GGGSSSAYWH QVLEPVQLRE GNVLFKSRKK EHSVLRLANQ LLKKLLCLRG SSSFSDDRWL LLQYQLEEYF SLNL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
  • 基因功能参考文献：
    1. Zfp127 is a novel regulator of Oct4, and may become a potent target to improve cellular reprogramming. PMID: 29335068
    2. Mkrn3, encoding a RING zinc-finger protein, is imprinted, with preferential expression from the paternal allele. PMID: 10196368
  • 组织特异性：
    Expressed in testis, brain, heart and kidney. Ubiquitously detected at low levels throughout the entire embryo, but expression is highest in the ventricular layers of the brain.
  • 数据库链接：

    KEGG: mmu:22652

    STRING: 10090.ENSMUSP00000091898

    UniGene: Mm.146