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  4. Recombinant Human Protein phosphatase 1 regulatory subunit 16A (PPP1R16A)

Recombinant Human Protein phosphatase 1 regulatory subunit 16A (PPP1R16A)

  • 中文名称：
    人PPP1R16A重组蛋白
  • 货号：
    CSB-YP839340HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人PPP1R16A重组蛋白
  • 货号：
    CSB-EP839340HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人PPP1R16A重组蛋白
  • 货号：
    CSB-EP839340HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人PPP1R16A重组蛋白
  • 货号：
    CSB-BP839340HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人PPP1R16A重组蛋白
  • 货号：
    CSB-MP839340HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PPP1R16A
  • Uniprot No.：
  • 别名：
    2900084E10Rik; Likley ortholog of mouse myosin phosphatase targeting subunit 3; MGC14333; Myosin phosphatase target subunit 3; Myosin phosphatase targeting subunit 3 ; Myosin phosphatase-targeting subunit 3; MYPT3 ; PP16A_HUMAN; PPP1R16A; Protein phosphatase 1 regulatory subunit 16A; Protein phosphatase 1, regulatory (inhibitor) subunit 16A; R75527
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-525
  • 氨基酸序列
    MAEHLELLAE MPMVGRMSTQ ERLKHAQKRR AQQVKMWAQA EKEAQGKKGP GERPRKEAAS QGLLKQVLFP PSVVLLEAAA RNDLEEVRQF LGSGVSPDLA NEDGLTALHQ CCIDDFREMV QQLLEAGANI NACDSECWTP LHAAATCGHL HLVELLIASG ANLLAVNTDG NMPYDLCDDE QTLDCLETAM ADRGITQDSI EAARAVPELR MLDDIRSRLQ AGADLHAPLD HGATLLHVAA ANGFSEAAAL LLEHRASLSA KDQDGWEPLH AAAYWGQVPL VELLVAHGAD LNAKSLMDET PLDVCGDEEV RAKLLELKHK HDALLRAQSR QRSLLRRRTS SAGSRGKVVR RVSLTQRTDL YRKQHAQEAI VWQQPPPTSP EPPEDNDDRQ TGAELRPPPP EEDNPEVVRP HNGRVGGSPV RHLYSKRLDR SVSYQLSPLD STTPHTLVHD KAHHTLADLK RQRAAAKLQR PPPEGPESPE TAEPGLPGDT VTPQPDCGFR AGGDPPLLKL TAPAVEAPVE RRPCC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Inhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates.
  • 基因功能参考文献：
    1. PPP1R16A gene expression is decreased in follicular variant of papillary thyroid carcinoma. PMID: 21509594
    2. analysis of a novel mechanism for the phosphorylation of MYPT3 by PKA and activation of the catalytic activity through direct interaction of a central region of MYPT3 with its N-terminal region PMID: 16920702
  • 亚细胞定位：
    Cell membrane; Lipid-anchor.
  • 数据库链接：

    HGNC: 14941

    OMIM: 609172

    KEGG: hsa:84988

    STRING: 9606.ENSP00000292539

    UniGene: Hs.521937