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Recombinant Drosophila melanogaster Paired box pox-neuro protein (Poxn)

  • 货号:
    CSB-YP338546DLU
  • 规格:
  • 来源:
    Yeast
  • 其他:
  • 货号:
    CSB-EP338546DLU
  • 规格:
  • 来源:
    E.coli
  • 其他:
  • 货号:
    CSB-EP338546DLU-B
  • 规格:
  • 来源:
    E.coli
  • 共轭:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 货号:
    CSB-BP338546DLU
  • 规格:
  • 来源:
    Baculovirus
  • 其他:
  • 货号:
    CSB-MP338546DLU
  • 规格:
  • 来源:
    Mammalian cell
  • 其他:

产品详情

  • 纯度:
    >85% (SDS-PAGE)
  • 基因名:
    Poxn
  • Uniprot No.:
  • 别名:
    Poxn; pox-n; CG8246; Paired box pox-neuro protein; Paired box neuronal protein
  • 种属:
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度:
    full length protein
  • 表达区域:
    1-425
  • 氨基酸序列
    MPHTGQAGVN QLGGVFVNGR PLPDCVRRRI VDLALCGVRP CDISRQLLVS HGCVSKILTR FYETGSIRPG SIGGSKTKQV ATPTVVKKII RLKEENSGMF AWEIREQLQQ QRVCDPSSVP SISSINRILR NSGLWTDEMT SSQQNAAAAA AAAAAAAHQA GSGPSNGYGG QAPPPPVTVA PPTPAATPSI ARYAKPPALM MNSAGEMPIK PAPKMPPSMG HGHSHGLNPN VSGLDLSYSA LHKHWLWNPS LLYYTQAHIQ AQAAASGGQF LPYAGGYLPH AMAAAAASST SALGGFTKSE SSIDLSTPGA AGDALSDCDS GKSSPAALSL TASGGGNGAG SAPEASPGST LSHSRKRNPY SIEELLKKPE KRLRLDSNRL ECLESSSCES SQDSPVAPPL ETPEDEDPAE AEEEQEEEDS VEVVN
  • 蛋白标签:
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

产品评价

靶点详情

  • 功能:
    Transcriptional regulator that specifies poly-innervated organs (chemosensory bristle). Also controls the number of neurons.
  • 基因功能参考文献:
    1. The paired box gene Pox neuro (Poxn) is expressed in two bilaterally symmetric neuronal clusters of the developing adult Drosophila brain, a protocerebral dorsal cluster (DC) and a deutocerebral ventral cluster (VC). The study shows that all cells that express Poxn in the developing brain are postmitotic neurons. Poxn is crucial for pathfinding both in the DC and VC. PMID: 28441464
    2. Pox neuro controls cell lineages that give rise to larval poly-innervated external sensory organs in Drosophila. PMID: 25446278
    3. Pox neuro has roles in Drosophila male courtship, fertility, segmentation of the leg disc and antennal disc, and development of the wing hinge PMID: 12421707
    4. expression in embryonic brain PMID: 12702651
    5. poxn is involved in suppressing bract formation near the chemosensory bristles. PMID: 15286997

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  • 亚细胞定位:
    Nucleus.
  • 组织特异性:
    Central and peripheral nervous systems.
  • 数据库链接:

    KEGG: dme:Dmel_CG8246

    STRING: 7227.FBpp0302942

    UniGene: Dm.4653