RGS12 Antibody
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货号:CSB-PA942986
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规格:¥1100
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图片:
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其他:
产品详情
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Uniprot No.:O14924
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基因名:RGS12
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别名:RGS12 antibody; Regulator of G-protein signaling 12 antibody; RGS12 antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Synthetic peptide of Human RGS12
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
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抗体亚型:IgG
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纯化方式:Antigen affinity purification
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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产品提供形式:Liquid
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应用范围:ELISA,WB
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推荐稀释比:
Application Recommended Dilution ELISA 1:1000-1:2000 WB 1:200-1:1000 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相关产品
靶点详情
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功能:Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form.; Behaves as a cell cycle-dependent transcriptional repressor, promoting inhibition of S-phase DNA synthesis.
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基因功能参考文献:
- Findings identify RGS12 as a candidate tumor-suppressor gene in AA prostate cancer, which acts by decreasing expression of AKT and MNX1, establishing a novel oncogenic axis in this disparate disease setting. PMID: 28611045
- Data support the notion that the Galpha, but not Gbetagamma, arm of the Gi/o signalling is involved in TRPC4 activation and unveil new roles for RGS and RGS12 in fine-tuning TRPC4 activities. PMID: 26987813
- RGS12 is essential for the terminal differentiation of osteoclasts induced by RANKL. PMID: 17042716
- shows chromosomal mapping information for human locus. PMID: 9168931
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亚细胞定位:Nucleus. Cytoplasm. Cell projection, dendrite. Cell junction, synapse.; [Isoform 5]: Nucleus matrix.
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组织特异性:Isoform 3 is brain specific.
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数据库链接:
HGNC: 9994
OMIM: 602512
KEGG: hsa:6002
STRING: 9606.ENSP00000339381
UniGene: Hs.527061
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