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DPYSL4 Antibody

  • 货号：
    CSB-PA006637
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of LOVO cells using CRMP-3 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    O14531
  • 基因名：
    DPYSL4
  • 别名：
    Collapsin response mediator protein 3 antibody; CRMP 3 antibody; CRMP-3 antibody; CRMP3 antibody; Dihydropyrimidinase like 4 antibody; Dihydropyrimidinase related protein 4 antibody; Dihydropyrimidinase-related protein 4 antibody; DPYL4_HUMAN antibody; DPYSL4 antibody; DRP 4 antibody; DRP-4 antibody; DRP4 antibody; ULIP 4 antibody; ULIP-4 antibody; ULIP4 antibody; UNC33 like phosphoprotein 4 antibody; UNC33-like phosphoprotein 4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human CRMP-3.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
  • 基因功能参考文献：
    1. DPYSL4 plays a key role in the tumor-suppressor function of p53 by regulating oxidative phosphorylation and the cellular energy supply via its association with mitochondrial supercomplexes, possibly linking to the pathophysiology of both cancer and obesity. PMID: 30061407
    2. DPYSL4 is a novel apoptosis-inducible factor controlled by p53 in response to DNA damage PMID: 20499313
    3. Aberrant expression of dihydropyrimidinase related proteins-2,-3 and -4 in fetal Down syndrome brain. PMID: 11771764
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Metallo-dependent hydrolases superfamily, Hydantoinase/dihydropyrimidinase family
  • 数据库链接：

    HGNC: 3016

    OMIM: 608407

    KEGG: hsa:10570

    STRING: 9606.ENSP00000339850

    UniGene: Hs.100058