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DDX54 Antibody

  • 货号：
    CSB-PA002109
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of Jurkat cells using DDX54 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q8TDD1
  • 基因名：
    DDX54
  • 别名：
    2410015A15Rik antibody; AI414901 antibody; ATP dependent RNA helicase DDX54 antibody; ATP-dependent RNA helicase DDX54 antibody; ATP-dependent RNA helicase DP97 antibody; DDX54 antibody; DDX54_HUMAN antibody; DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 antibody; DEAD box helicase 54 antibody; DEAD box protein 54 antibody; DEAD box RNA helicase 97 kDa antibody; DP97 antibody; MGC2835 antibody; RGD1562539 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human DDX54.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors.
  • 基因功能参考文献：
    1. Ddx54 plays an important role in central nervous system myelination, presumably in myelin sheath formation after the differentiation of oligodendrocytes. PMID: 23239230
    2. DP97 was found to be a gene (or promoter)-selective co-activator for hCAR PMID: 22910411
    3. Identifies DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 (locus 79039) as a novel nucleolar protein in HeLa cells. PMID: 11790298
    4. Identifies dead box polypeptide 54 as a 14-3-3-binding protein. PMID: 16260042
    5. Identifies DEAD box polypeptide 54 (similar to RIKEN cDNA 2410015A15 gene) as one of 213 different nucleolar proteins in HeLa cells. PMID: 12429849
    6. Kinetic analysis of DEAD box helicases, including DEAD box polypeptide 54, in response to transcription inhibition. PMID: 15635413
    7. Includes the identification of DEAD box polypeptide 54 phosphopeptides following the stimulation of HeLa cells with epidermal growth factor. PMID: 17081983

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  • 亚细胞定位：
    Nucleus, nucleolus.
  • 蛋白家族：
    DEAD box helicase family, DDX54/DBP10 subfamily
  • 组织特异性：
    Expressed in the fallopian tube, cervix and uterus. Also expressed in the brain.
  • 数据库链接：

    HGNC: 20084

    OMIM: 611665

    KEGG: hsa:79039

    STRING: 9606.ENSP00000323858

    UniGene: Hs.506861